The following stories appear in full on today's Vidyya Medical News Service Web site.
The FDA and Bristol Myers Squibb are warning health care professionals that pregnant women may be at increased risk of fatal lactic acidosis when prescribed the combination of the HIV drugs stavudine (Zerit) and didanosine (Videx or Videx EC) with other antiretroviral agents.
For more information: FDA/Bristol Myers Squibb Issues Caution For HIV Combination Therapy With Zerit And Videx In Pregnant Women
Videx (didanosine) in combination with other antiretroviral agents is indicated for the treatment of HIV-1 infection. Videx (didanosine) does not cure HIV infection or prevent passing HIV to others. Fatal and nonfatal pancreatitis has occurred when Videx was used alone or as part of a combination regimen. Patients treated with Videx in a combination regimen that includes stavudine with or without hydroxyurea may be at increased risk for pancreatitis. Get the full prescribing information for Videx in today's issue.
For more information: Prescribing Information: Videx
Zerit (stavudine), in combination with other antiretroviral agents, is indicated for the treatment of HIV-1 infection. Zerit (stavudine) does not cure HIV infection or prevent passing HIV to others. There have been cases of lactic acid buildup in the blood and enlarged liver, including fatal cases. Fatal and nonfatal pancreatitis has occurred when Zerit was part of a combination regimen that included didanosine, with or without hydroxyurea. Zerit may cause numbness, tingling or pain in the hands or feet (neuropathy). This risk is increased in patients with HIV disease or a history of neuropathy. If this occurs, lowering the dose or stopping Zerit to improve symptoms. Patients treated with Zerit in combination with other medicines that may cause similar side effects may have a higher chance of developing these side effects. The most frequent side effects associated with Zerit are nausea, diarrhea, headache, rash, and neuropathy. Vidyya has the full prescribing information for Zerit available for you in today's issue.
For more information: Prescribing Information: Ziret
A massive injection of £200 million is set to ensure that NHS decontamination and sterilization services are modernized so that all surgical equipment in hospitals is cleaned and sterilised to the highest possible standard to protect patients from a theoretical risk of variant Creutzfeldt Jakob Disease (vCJD).
For more information: UK NHS Invests In Equipment To Cut Risk Of CJD Transmission
On 03 January 2001, the UK Department of Health issued the latest information about the numbers of known cases of Creutzfeldt Jakob disease. The
position on variant Creutzfeldt Jakob disease (vCJD) - the form of the disease thought to be linked to Bovine Spongiform Encephalitis. In the year 2000 there were 72 total cases, down from the previous three years. As the world begins to worry about vCJD, Vidyya will keep an eye on the statistics coming from the UK and report on the newly diagnosed cases in France.
Latest Creutzfeldt Jakob Disease (CJD & vCJD) Statistics
Today's Vidyya articles are:
As always, we hope you enjoy the issue.