The following stories appear in full on today's Vidyya Medical News Service Web site.
Acne is a disorder of the skinís oil glands (sebaceous glands) that results in plugged pores and outbreaks of lesions commonly called pimples or zits. Acne lesions usually occur on the face, neck, back, chest, and shoulders. Nearly 17 million people in the United States have acne, making it the most common skin disease. Although acne is not a serious health threat, severe acne can lead to disfiguring, permanent scarring, which can be upsetting for people who suffer from the disorder.
For more information: Questions And Answers: Acne
A popular acne medication has fallen out of public favor over the last year as it has been traced to everything from birth defects to teen suicide. As a result, the manufacturer has carefully rewritten the drug's prescribing information. Get the most recently updated information in today's issue.
For more information: Prescribing Information (Revised): Accutane
Because serious birth-defects have been traced to the anti-acne medication, Accutane, the following consent form was developed. Print the form and distribute it as you deem necessary.
For more information: Accutane: Revised Informed Consent Forms
Accutane is used to treat the most severe form of acne (nodular acne) that cannot be cleared up by any other acne treatments, including antibiotics. In severe nodular acne, many red, swollen, tender lumps form in the skin. These can be the size of pencil erasers or larger. If untreated, nodular acne can lead to permanent scars. However, because Accutane can have serious side effects, the medication guide in today's issue can help patients understand when it is appropriate to take the medication and what types of side effects they can expect.
For more information: Information For Patients: Accutane Medication Guide
Accutane is approved by the Food and Drug Administration (FDA) to treat severe, recalcitrant nodular acne. As this issue illustrates, it is also a known human teratogen that can cause multiple major malformations. Embryopathy associated with the mother's exposure to isotretinoin during the first trimester of pregnancy includes craniofacial, cardiac, thymic, and central nervous system malformations. In response to FDA recommendations, the manufacturer began a pregnancy-prevention program (PPP) in 1988 that included educational materials for physicians and patients and offered women reimbursement for contraceptive counseling by a physician.
For more information: CDC Report: Accutane Exposed Pregnancies
Today's Vidyya articles are:
As always, we hope you enjoy the issue.