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Vidyya, from the Sanskrit "vaidya," a practitioner who has come to understand the science of life.

Volume 2 Published - 14:00 UTC    08:00 EST    09-February-2001      
Issue 40 Next Update - 14:00 UTC 08:00 EST    10-February-2001      

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Vidyya Medical News Service For 09-February-2001:

The following stories appear in full on today's Vidyya Medical News Service Web site.

The Arthritis Advisory Committee to the US Food and Drug Administration (FDA) has provided guidance to the FDA that the labels for both Vioxx (rofecoxib) and Celebrex (celecoxib capsules) should reflect data showing gastrointestinal safety advantages versus the specific comparator NSAIDs studied.

For more information: FDA Advisory Committee Acknowledges The GI Safety Data For Both COX-2 Inhibitors, Vioxx® And Celebrex®

Irinotecan, approved for first-line therapy in patients with metastatic colorectal cancer, has been shown to increase progression-free survival, delay tumor growth and also is showing potential in other cancer types.

For more information: The Present And Future Of Cancer Therapy: Versatile Anti-Cancer Drug Irinotecan

Though currently approved as chemotherapy for colorectal cancers, irinotecan may have an important role in the treatment of a number of other cancers, including small cell lung cancer and non-small cell lung cancer, esophageal cancer, gastric cancer, cervical cancer, malignant brain tumors and ovarian cancer, as well as pancreatic cancer. You'll need the prescribing information, and you can get it in today's Vidyya.

For more information: Prescribing Information: Irinotecan (Camptosar ®)

Parents may be able to breathe a sigh of relief. A major statistical analysis of UK children, published on the website of the British Medical Journal, has found that there appears to be no clear link between MMR and the of autism cases. According to the report, the number of cases has continued to rise even though MMR coverage has remained roughly the same--if MMR was the cause of illness, say the experts, the number of autism diagnoses would have levelled off. No further explanation has been offered what is causing the increasted rate of autism.

For more information: Major Study Says MMR Vaccine Does Not Cause Autism

Tamoxifen has been shown to reduce the incidence of breast cancer in healthy women at high risk of developing the disease. However, the impact of the drug on heart disease has been the subject of much debate.

For more information: Mixed Bag: Anti-Cancer Drug, Tamoxifen, May Have Cardioprotective Effects

today's Vidyya articles are:

As always, we hope you enjoy the issue.

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Editor: Susan K. Boyer, RN
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