Cancell is also known as Entelev, Sheridan's Formula, Jim's Juice, Crocinic Acid,
JS-114, JS-101, 126-F, and Cantron. It has been promoted as a therapy for cancer and a wide range of other diseases. The US Food and Drug Administration has listed the components of Cancell as inositol, nitric acid, sodium sulfite, potassium hydroxide, sulfuric acid, and catechol. Cancell can be administered orally or rectally. It can also be applied to the skin of the wrist or the ball of the foot.
Cancell was developed by James V. Sheridan, a former researcher at the Michigan Cancer Center, in the 1930s. Mr. Sheridan and his associate, Edward J. Sopcak, offered the mixture free of charge to any seriously ill patient who requested it.
The principal manufacturers of Cancell state that they have performed numerous animal experiments with the mixture, and that it has been used by many cancer patients. However, these findings have not been published in peer-reviewed, scientific journals, and no clinical trials (research studies with patients) of Cancell have been conducted. The National Cancer Institute (NCI) has evaluated Cancell in the laboratory and in animal studies and found that it had no effect on cancer cells.
Because studies of Cancell have not shown it to be effective in treating cancer, it has not been approved by the US Food and Drug Administration (FDA). In 1989, the FDA obtained a
permanent injunction against the manufacturers of Cancell. The injunction prohibited the manufacture or distribution of the product. The Cancell mixture is reportedly being sold under various names as a dietary supplement in health food stores.
More detailed information about Cancell can be found in the National Cancer Institute's PDQ database for cancer information. This information is available from the NCI's Cancer Information Service (CIS) at 1–800–4–CANCER (1–800–422–6237), or on the CancerNet Web site at http://cancernet.nci.nih.gov/cam/cancell.htm on the Internet.