||Prescribing Information: Slo-Niacin ® Polygel ® Controlled-Release Niacin
Dietary Supplement For Use When Tolerability Is A Concern
- Slo-Niacin® Tablets are manufactured
utilizing a unique, patented polygel® controlled-release delivery system.
This exclusive technology assures the gradual and measured release of niacin
(nicotinic acid) and is designed to reduce the incidence of flushing and itching
commonly associated with niacin use. Slo-Niacin® Tablets are available
in 250 mg, 500 mg, and 750 mg strengths.
- SUGGESTED USE
- Slo-Niacin® is a member of
the vitamin B-complex group (nicotinic acid, vitamin B-3) and is suggested
as a dietary supplement. This product has the advantage of a slower release
of niacin than conventional dosage forms. This may permit its use by those
who do not tolerate immediate-release tablets.
- 250 mg: Adults -- one Slo-Niacin®
Tablet morning or evening, or as directed by a physician.
500 mg: Adults -- one Slo-Niacin® Tablet morning or evening, or as directed
by a physician.
750 mg: Adults -- one-half Slo-Niacin® Tablet morning or evening, or as
directed by a physician.
Before using more than 500 mg daily, consult a physician.
Note: Slo-Niacin® Tablets may be broken on the score line, but should
not be crushed or chewed. The inactive matrix of the tablet is not absorbed
and may be excreted intact in the stool.
Store at controlled room temperature, 15-30o
- Niacin may cause temporary flushing,
itching and tingling, feelings of warmth and headache, particularly when beginning,
increasing amount or changing brand of niacin. These effects seldom require
discontinuing niacin use. Skin rash, upset stomach, and low blood pressure
when standing are less common symptoms; if they persist, contact a physician.
- Slo-Niacin® Tablets should
not be used by persons with a known sensitivity or allergy to niacin. Persons
with heart disease, particularly those who have recurrent chest pain (angina)
or who recently suffered a heart attack, should take niacin only under the
supervision of a physician. Persons taking high blood pressure or cholesterol-lowering
drugs should contact a physician before taking niacin because of possible
interactions. Do not take niacin unless recommended by and taken under the
supervision of a physician if you have any of the following conditions: gallbladder
disease, gout, arterial bleeding, glaucoma, diabetes, impaired liver function,
peptic ulcer, pregnancy or lactating women. Increased uric acid and glucose
levels and abnormal liver function tests have been reported in persons taking
daily doses of 500 mg or more of niacin.
Discontinue use and consult a physician immediately if any of the following
symptoms occur: persistent flu-like symptoms (nausea, vomiting, a general
"not well" feeling); loss of appetite; a decrease in urine output
associated with dark-colored urine; muscle discomfort such as tender, swollen
muscles or muscle weakness; irregular heartbeat; or cloudy or blurry vision.
Keep out of reach of children.
- 250 mg niacin (nicotinic acid),
supplying 1,250% of the Reference Daily Intake (RDI) for niacin.
500 mg niacin (nicotinic acid), supplying 2,500% of the Reference Daily Intake
(RDI) for niacin.
750 mg niacin (nicotinic acid), supplying 3,750% of the Reference Daily Intake
(RDI) for niacin.
Each tablet also contains: cellulose polymer derivative, vegetable stearine,
magnesium stearate, silicon dioxide, glyceryl behenate, and FD&C Red No. 40.
UPSHER-SMITH LABORATORIES, INC.
Minneapolis, MN 55447
U.S. Patents No. 5,126,145 and 5,268,181.
Vidyya. Home |
Ex Libris |
Subscription Information |
About Vidyya |
Vidyya Archives |
Editor: Susan K. Boyer, RN
© Vidyya. All rights reserved.