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Back To Vidyya Prescribing Information: Slo-Niacin ® Polygel ® Controlled-Release Niacin

Dietary Supplement For Use When Tolerability Is A Concern

Slo-Niacin® Tablets are manufactured utilizing a unique, patented polygel® controlled-release delivery system. This exclusive technology assures the gradual and measured release of niacin (nicotinic acid) and is designed to reduce the incidence of flushing and itching commonly associated with niacin use. Slo-Niacin® Tablets are available in 250 mg, 500 mg, and 750 mg strengths.
Slo-Niacin® is a member of the vitamin B-complex group (nicotinic acid, vitamin B-3) and is suggested as a dietary supplement. This product has the advantage of a slower release of niacin than conventional dosage forms. This may permit its use by those who do not tolerate immediate-release tablets.
250 mg: Adults -- one Slo-Niacin® Tablet morning or evening, or as directed by a physician.

500 mg: Adults -- one Slo-Niacin® Tablet morning or evening, or as directed by a physician.

750 mg: Adults -- one-half Slo-Niacin® Tablet morning or evening, or as directed by a physician.

Before using more than 500 mg daily, consult a physician.

Note: Slo-Niacin® Tablets may be broken on the score line, but should not be crushed or chewed. The inactive matrix of the tablet is not absorbed and may be excreted intact in the stool.

Store at controlled room temperature, 15-30o C(59-86o F)
Niacin may cause temporary flushing, itching and tingling, feelings of warmth and headache, particularly when beginning, increasing amount or changing brand of niacin. These effects seldom require discontinuing niacin use. Skin rash, upset stomach, and low blood pressure when standing are less common symptoms; if they persist, contact a physician.
Slo-Niacin® Tablets should not be used by persons with a known sensitivity or allergy to niacin. Persons with heart disease, particularly those who have recurrent chest pain (angina) or who recently suffered a heart attack, should take niacin only under the supervision of a physician. Persons taking high blood pressure or cholesterol-lowering drugs should contact a physician before taking niacin because of possible interactions. Do not take niacin unless recommended by and taken under the supervision of a physician if you have any of the following conditions: gallbladder disease, gout, arterial bleeding, glaucoma, diabetes, impaired liver function, peptic ulcer, pregnancy or lactating women. Increased uric acid and glucose levels and abnormal liver function tests have been reported in persons taking daily doses of 500 mg or more of niacin.

Discontinue use and consult a physician immediately if any of the following symptoms occur: persistent flu-like symptoms (nausea, vomiting, a general "not well" feeling); loss of appetite; a decrease in urine output associated with dark-colored urine; muscle discomfort such as tender, swollen muscles or muscle weakness; irregular heartbeat; or cloudy or blurry vision.

Keep out of reach of children.
250 mg niacin (nicotinic acid), supplying 1,250% of the Reference Daily Intake (RDI) for niacin.

500 mg niacin (nicotinic acid), supplying 2,500% of the Reference Daily Intake (RDI) for niacin.

750 mg niacin (nicotinic acid), supplying 3,750% of the Reference Daily Intake (RDI) for niacin.

Each tablet also contains: cellulose polymer derivative, vegetable stearine, magnesium stearate, silicon dioxide, glyceryl behenate, and FD&C Red No. 40.

Minneapolis, MN 55447
U.S. Patents No. 5,126,145 and 5,268,181.
Rev. 0198

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