The following stories appear in full on Today's Vidyya Medical News Service Web site.
An international study published Friday, 23 March 2001 in The Lancet shows that a well established drug -- fenofibrate -- significantly reduces the risk of atherosclerosis -- the leading cause of potentially fatal events in millions of people with type 2 diabetes.
For more information: Fenofibrate Significantly Reduces Risk Of Atherosclerosis
Six children have died of measles and 15 others are in critical condition after an outbreak of measles in Ugandan capital Kampala. Elsewhere, the World Health Organization has received preliminary reports of 23 hospitalized cases of plague, including 3 deaths in Petauke district of Zambia.
For more information: Measles Toll Reaches Six In Ugandan Capital: Plague Reported In Zambia
NIDDK scientists and their collaborators have discovered that a protein called M3 muscarinic acetylcholine receptor helps regulate how much animals eat. The findings, which appear in the 8 March 2001, issue of Nature, highlight just how complex the brain chemistry governing food intake is.
For more information: NIDDK Team Uncovers A Novel Pathway That Controls Eating
Fenofibrate lowers elevated serum lipids by decreasing the low density lipoprotein (LDL) fraction rich in cholesterol and the very low density lipoprotein (VLDL) fraction rich in triglycerides. In addition, fenofibrate increases the high density lipoprotein (HDL) cholesterol fraction. Fenofibrate appears to have a greater depressant effect on the very low density lipoproteins (VLDL) than on the low density lipoproteins (LDL). Therapeutic doses of fenofibrate produce variable elevations of HDL cholesterol, a reduction in the content of the total low density lipoproteins cholesterol, and a substantial reduction in the triglyceride content of very low density lipoproteins.
For more information: Prescribing Information: Fenofibrate (Lipidil ®)
The United States has aggressive BSE surveillance and prevention programs in place. FDA's restrictions on certain animal feed ingredients and its import alerts on cattle products are a critical part of this program. In addition, USDA has an import ban on certain cattle and cattle products, and CDC has established surveillance and investigation programs for suspected human TSE cases. USDA's Animal and Plant Health Inspection Service (APHIS) introduced import restrictions in 1989, when it banned the import of all live ruminants (cud-chewing animals, such as cows, sheep, and goats) from the UK.
For more information: BSE: Background, Current Concerns, And US Response
Today's Vidyya articles are:
As always, we hope you enjoy the issue.