The following stories appear in full on Today's Vidyya Medical News Service Web site.
An ongoing Phase I clinical trial at the National Cancer Institute (NCI) reports that 11 of 16 patients with chemotherapy-resistant hairy cell leukemia (HCL), an uncommon form of B-cell cancer, had complete remissions lasting up to 18 months, most without major side effects, when treated with a new immunotoxin-based drug. The Phase I trial was presented at a minisymposium during the American Association for Cancer Research's annual meeting in New Orleans, 24-28 March 2001. The unusually high response rates lead researchers to have high hopes for the use of this drug in HCL, and possibly in other patients.
For more information: High Response Rate Of Hairy Cell Leukemia Patients To Immunotoxin Treatment Raises Hopes
Today's Vidyya contains the second report of the US Surgeon General devoted to women and smoking. The first was published in 1980, 16 years after the initial landmark report on smoking and health of the Advisory Committee to the Surgeon General appeared in 1964. The 1964 report summarized the accumulated evidence that demonstrated that smoking was a cause of human cancer and other diseases. Most of the early evidence was based on men. In the decades since, numerous studies have expanded the breadth and depth of what is known about the health consequences of smoking among women, about historical and contemporary patterns of smoking in demographic subgroups of the female population, about factors that affect initiation and maintenance of smoking among women and about interventions to assist women to quit smoking.
For more information: The Surgeon General's Report On Women And Smoking: Executive Summary
Women now account for 39 percent of all smoking-related deaths each year in the United States, a proportion that has more than doubled since 1965, according to a report on women and smoking released today by Surgeon General David Satcher. The report concludes that the increased likelihood of lung cancer, cardiovascular disease, and reproductive health problems among female smokers makes tobacco use a serious womenís health issue.
For more information: New Surgeon Generalís Report Highlights The Health Impact Of Smoking
Get the facts about women and smoking. Cigarette smoking is the major cause of lung cancer among women. About 90% of all lung cancer deaths among US women smokers are attributable to smoking. Since 1950, lung cancer mortality rates for U.S. women have increased an estimated 600%. In 1987, lung cancer surpassed breast cancer to become the leading cause of cancer death among US women. In 2000, about 27,000 more women died of lung cancer (67,600) than breast cancer (40,800).
For more information: Fact Sheet: Health Consequence of Tobacco Use Among Women
Smoking during pregnancy is associated with increased risk for premature rupture of membranes, abruptio placentae, and placenta previal, which can cause massive hemorrhaging during delivery; smoking is also associated with a modest increase in risk for preterm delivery.
For more information: Fact Sheet: Tobacco Use and Reproductive Outcomes
Today's Vidyya articles are:
As always, we hope you enjoy the issue.