A class of nutrients, isothiocyanates, found only in
cruciferous vegetables -- broccoli, cauliflower, cabbage,
watercress, bok choy, among others -- was protective against
lung cancer in the study of a sample of 18,244 males, 45-64
years old, in Shanghai, China. The study also showed a
unique gene-diet interaction. Subjects genetically
deficient in an enzyme (GSTM1) that quickly eliminates
isothiocyanates (ITCs) from the body got the most benefit
from cruciferous vegetables, presumably because ITCs stayed
around longer to confer their protective effect.
Since the subject of health eating was in the news today, Vidyya went in search of guidelines on the subject. Counseling adults and children over age 2 to limit dietary intake of fat (especially saturated fat) and cholesterol, maintain caloric balance in their diet, and emphasize foods containing fiber (i.e., fruits, vegetables, grain products) is recommended by the US Preventive Services Task Force. The full guidelines are available in this Vidyya.
In drug news, the FDA today proposed that all systemic antibacterial drug products intended for human use contain additional labeling information about the emergence of drug-resistant bacterial strains. New resistant strains are a major threat to future public health.
On the subject of drug resistance, for three decades, vancomycin has been the powerhouse therapy for certain life-threatening bacteria. Research now shows that with the widespread use of vancomycin, vancomycin-resistant organisms have emerged. Data from the Synercid as an Alternative to Vancomycin in Staph (S.A.V.S.) study presented at the 40th annual meeting of the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) shows that Synercid® (quinupristin/dalfopristin) I.V. is a potential alternative in cases where patients with a staphylococcal infection were unable to tolerate vancomycin's side effects, and where vancomycin did not eradicate the bacteria.
And finally, in cardiology news, two results from routine exercise
tests can be combined to predict risk of death from all causes in adults over a five-year period, according to a Cleveland Clinic study published today in the Journal of the American Medical Association.
The articles in today's Vidyya are:
As always, we hope you enjoy the issue.