The following stories appear in full on today's Vidyya Medical News Service Web site.
Proteins that help clean and organize the inside of certain T cells may assist HIV in spreading through the body, scientists from the National
Institute of Allergy and Infectious Diseases (NIAID) report in the November
21 issue of the Proceedings of the National Academy of Sciences. The new report, which complements studies by two other laboratories, is the first to implicate a collection of housekeeping proteins, collectively called the
ubiquitin-proteasome system, in spreading HIV from one cell to another.
National Cancer Institute (NCI) researchers and their collaborators have developed a laboratory model, which uses skin tissue, that should serve as a reliable tool for testing agents used topically during sexual intercourse to fight off HIV infection. To date, no available tissue culture models have proven adequate for preclinical testing of these agents, called microbicides. In the absence of an effective AIDS vaccine, microbicides are being developed to help stem the worldwide spread of AIDS. The new model for testing microbicdes is described in the November 20, 2000, issue of the Journal of Experimental Medicine.
The Nation has now entered the twenty-first century, but the fundamental challenge facing the CDC is the same as it was in its early days over 50 years ago—improving the quality of people’s lives by preventing disease, injury, and disability. A booklet in today's issue describes, in concise terms, key indicators used in measuring the Nation’s health status, current health concerns of the public, and the organization and activities of CDC in the years 2000/2001.
A new technique that uses pulses of energy to destroy malfunctioning heart cells can cure both episodic and chronic irregular heartbeats known as atrial fibrillation, Italian researchers report in today's Circulation: Journal of the American Heart Association.
An overview by a Yale researcher of four studies examining the use of aspirin and the reduction of heart attacks in persons with no previous history of cardiovascular disease shows aspirin remains a good preventive measure.
As always, we hope you enjoy the issue.