Brain changes accompany cocaine withdrawal and craving
Researchers have found that brain levels of a protein receptor rise, along with certain drug-seeking behaviors, after rats lose their access to cocaine. The finding may help explain why cocaine craving intensifies in the weeks and months after drug use ends. The research may also aid development of new drugs for preventing relapse.
Cocaine is a powerfully addictive stimulant drug. The powdered, hydrochloride salt form of cocaine can be snorted or dissolved in water and injected. Crack is cocaine that has not been neutralized by an acid to make the hydrochloride salt. This form of cocaine comes in a rock crystal that can be heated and its vapors smoked. The term "crack" refers to the crackling sound heard when it is heated. more
Hunger hormone increases during stress, may have antidepressant effect
New research at UT Southwestern Medical Center may explain why some people who are stressed or depressed overeat. more
Some patients may not need insulin for long-term control of type 2 diabetes
Some patients with type 2 diabetes can control their disease for years yet avoid insulin injections by using multiple classes of oral diabetic medications, a new study found. The results were presented Sunday, June 15, at The Endocrine Society's 90th Annual Meeting in San Francisco. more
Stem cell researchers give old muscle new pep
Old muscle got a shot of youthful vigor in a stem cell experiment by bioengineers at the University of California, Berkeley, setting the path for research on new treatments for age-related degenerative conditions such as muscle atrophy or Alzheimer's and Parkinson's diseases. more
Estrogen therapy helps or hurts the brain depending on reproductive status
Estrogen therapy may limit stroke damage if started close to, but not long after reproductive cycles are over, according to a new animal study. The results were presented Sunday, June 15, at The Endocrine Society's 90th Annual Meeting in San Francisco.
How Montezuma gets his revenge
Every year, about 500 million people worldwide are infected with the parasite that causes dysentery, a global medical burden that among infectious diseases is second only to malaria. In a new study appearing in the June 15 issue of Genes and Development, Johns Hopkins researchers may have found a way to ease this burden by discovering a new enzyme that may help the dysentery-causing amoeba evade the immune system. more
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