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Ex Libris
Evidence Based Medicine Web Sites

ACP Journal Club

   ACP Journal Club's general purpose is to select from the biomedical literature those articles reporting studies and reviews that warrant immediate attention by physicians attempting to keep pace with important advances in internal medicine.

Aggressive Research Intelligence Facility (ARIF)

   ARIF is a specialist unit of four people based at the University of Birmingham (UK). Their role is to improve the incorporation of research findings into population level health care decisions in the NHS in the West Midlands region. They help health care workers access and interpret research evidence, particularly systematic reviews of research, in response to particular problems.

Australian Safety and Efficacy Register of New Interventional Procedures - Surgical (ASERNIP-S)

   ASERNIP-S was created in 1998 to address the need for the establishment of a body to assess new surgical procedures and technologies. The ASERNIP-S Web site contains project information including details of the procedures currently being studied. Reports of completed assessments are also available.


   Bandolier is produced monthly in Oxford for the NHS R∓mp;D Directorate. It contains bullet points (hence Bandolier) of evidence-based medicine. Internet access is free, though it runs some months behind. Subscription to the printed version of Bandolier costs £36 per year (UK) and £72 overseas.


   An authorized Spanish language version of Bandolier.

Bedside Diagnosis

   This site is a Web-searchable, annotated, bibliography of the available literature on physical examination and interviewing. The site is sponsored by the American College of Physicians-American Society of Internal Medicine (ACP-ASIM).

Canadian Centres for Health Evidence ( principal task of Centres of Health Evidence (CHE) is to package, disseminate, and present health knowledge in ways that facilitate its optimum use.

CASP - Critical Appraisal Skills Programme

   CASP is a UK project that aims to help health service decision makers and those that seek to influence the decision makers develop skills to find, critically appraise and change practice in line with evidence of effectiveness. These skills promote the delivery of evidence-based healthcare. At the heart of CASP's work is a cascade of half day workshops where participants learn through going on an interactive journey. CASP introduces people to the ideas of evidence-based healthcare and, through critical appraisal of systematic reviews, introduces people to the related ideas of the Cochrane Collaboration. CASP is developing an interactive CD-ROM, to be used in conjunction with workshops, video conferencing, as a stand alone package or to reinforce learning, thereby taking these skills to a wider audience and giving opportunities for independent practice or learning.

Centre for Clinical Effectiveness

   The Centre aims to enhance patient outcomes through the clinical application of the best available evidence. It undertakes teaching, research and answers requests for evidence from the staff of the Southern Health Care Network, Melbourne, Australia.

Centre for Evidence Based Child Health

  The overall aim of the Centre is to increase the provision of effective and efficient child health care through an educational programme for health professionals. Introductory seminars, short courses, MSc modules and training secondments are offered to paediatricians, nurses, general practitioners, healthcare purchasers and others involved in child health.

Centre for Evidence Based Dentistry

  The Centre for Evidence-based Dentistry is an independent body whose aim is to promote evidence-based dentistry world-wide. The Centre is linked to the Institute of Health Sciences in Oxford and by this link with a number of other initiatives designed to promote evidence-based clinical practice.

Centre for Evidence-Based Medicine

   The first of several centres around the UK whose broad aim is to promote evidence-based health care and provide support and resources to anyone who wants to make use of them.

Centre for Evidence-Based Medicine - EBM Toolbox

  An assortment of materials which are very useful for practitioners of EBM. You'll find statistical tools and much more.

Centre for Evidence Based Medicine (Mount Sinai)

  The goal of this Website is to help develop, disseminate, and evaluate resources that can be used to practise and teach EBM for undergraduate, postgraduate and continuing education for health care professionals from a variety of clinical disciplines.This site also serves as a support for the book entitled, Evidence-based Medicine: How to practice and teach EBM by David L. Sackett, et. al. Like many of the EBM sites, this one is rich in resources.

Centre for Evidence-based Mental Health

   This Website aims to support all mental health professionals in their everyday practice; providing a portal to high quality evidence based mental health (EBMH) information, as well as a range of teaching materials. The site is regularly updated (every Friday at 6pm GMT), and the most recent additions are highlighted on the homepage. It is a robust site for the mental health profession.

Centre for Evidence Based Nursing

   The Centre for Evidence Based Nursing (CEBN) is concerned with furthering EBN through education, research and development. Research activities: producing reliable research evidence for clinical nursing, researching how nurses in practice use their clinical expertise and the evaluation of the impact of teaching EBN on clinical practice and organizations.

Centre for Evidence-Based Pathology

   Evidence-based Pathology (EBP) aims to advance clinical diagnosis, classification and prognosis of disease through researching and disseminating generalisable, new knowledge which meets standards of critical review, on clinically effective practice of laboratory investigation.

Centre for Evidence Based Pharmacotherapy

   The Centre for Evidence-Based Pharmacotherapy (CEBP) was set up in July 1995 to undertake research in the methodology of medicines assessment, pharmacoepidemiology and pharmacoeconomics and to undertake such studies. The importance of these areas of research is being increasingly recognised by both governments and pharmaceutical companies.

Centre for Evidence Based Physiotherapy

   The Centre of Evidence-Based Physiotherapy was established by a small group of clinical and academic physiotherapists. It is based at the School of Physiotherapy at the University of Sydney. The Centre's mission is to maximise the effectiveness of physiotherapy services by facilitating the clinical application of the best available evidence.

Centre for Reviews and Dissemination

   The Centre for Reviews and Dissemination (CRD), by offering rigorous and systematic reviews on selected topics, a database of good quality reviews, a dissemination service and an information service, helps to promote research based practice in the UK NHS.

Centre for Evidence-Based Social Services

   This Centre has been jointly funded by The Department of Health and a consortium of Social Services Departments in the South and South West of England with the main aim of ensuring that decisions taken at all levels in social services are informed by trends from good-quality research.

Centre for Statistics in Medicine

   The Centre for Statistics in Medicine (CSM) was established in the new Institute of Health Sciences in Oxford in September 1995. It incorporates the Medical Statistics Group of the Imperial Cancer Research Fund (ICRF) and is affiliated to the Nuffield Department of Clinical Medicine (University of Oxford).

Centres for Health Evidence

   You'll find loads of EBH resources at this site--including critical appraisal worksheets and the JAMA EBH Guides.

CHAIN - Contact Help Advice Information Network for Effective Health Care

   C.H.A.I.N. is a contact database for health care professionals interested in clinical effectiveness and evidence based health care.

Clinical Assessment of the Reliability of the Exam (CARE)

   An on-going internet-based research project in the important field of clinical examination.

Clinical Examination Research Interest Group

   A special interest group of the Society for General Internal Medicine responsible for the set of Rational Clinical Examination Guides published in JAMA between 1992-1999. The group is primarily interested in gathering clinical evidence on physical examination.

Clinical Evidence

   Clinical Evidence is a six monthly, updated compendium of evidence on the effects of common clinical interventions, published by the BMJ Publishing Group. It provides a concise account of the current state of knowledge, ignorance, and uncertainty about the prevention and treatment of a wide range of clinical conditions based on thorough searches of the literature. It is not a textbook of medicine nor a book of guidelines. It summarises the best available evidence, and where there is no good evidence, it says so.

Clinical Practice Guideline Catalogue

   Guideline collection maintained by the Alberta Medical Association.

Clinical Practice Guidelines Infobase

   These guidelines are produced or endorsed in Canada by a national, provincial or territorial medical or health organization, professional society, government agency or expert panel. An excellent resource of full-text practice guidelines.

Clinical Trial Managers Association

   This web site is a meeting place for organizers of clinical trials - to disseminate ideas and educational materials, and increase our knowledge base - a quality-assured source of support, a community.

Cochrane Collaboration

   This is the grandfather of all EBM sites. The Cochrane Collaboration facilitates the creation, review, maintenance and dissemination of systematic overviews of the effects of health care. You must subscribe to the best information on the site, but review abstracts are available for free. This is the main site of the Cochrane Collaboration. There are many international sites available from this point. This was once the pearl of all EBM knowledge, but other sites are fast catching up, and offering access to all information for free.

Cochrane Database of Systematic Reviews

   This site contains the abstracts of reviews and the titles of reviews in progress. The database can be searched for specific words/phrases or browsed by Collaborative Review Group. Access to the full reviews and protocols is only available via subscription.

Controlled Trials in History

   The Royal College of Surgeons of Edinburgh brings together many notable studies from the histories of controlled trials. Other topics include methods for the control of selection biases and control of observer biases and there is a detailed bibliography.

Core Library of Evidence Based Practice

   This Virtual Library has been put together by assembling links to full text documents on all aspects of Evidence Based Practice. Further suggestions are invited.

Critique et Pratique (French Language)

   Each week, members of the Laval University Family Medicine Department (Québec, Canada) summarize and comment on two articles from recent issues of medical journals. The commentary is based on evidence-based medicine principles and on the evaluation of the impact of research on medical practice.

Definitions of Evidence Based Medicine/Healthcare/Practice

   This is a ScHARR Compilation page of definitions of Evidence Based Medicine etcetera from published articles, reports books and Web pages.

EBM Toolbox

   Not to be confused with the Centre for Evidence Based Medicine's EBM Toolbox. This Canadian-based collection of resources provides excellent support of EBM. Be sure to check out the "user guides" and "work sheets" and other hands-on resources.

Effective Health Care Bulletins

  Effective Health Care is a bi-monthly bulletin for decision makers which examines the effectiveness of a variety of health care interventions. Effective Health Care bulletins are based on a systematic review and synthesis of research on the clinical effectiveness, cost-effectiveness and acceptability of health service interventions. This is carried out by a research team using established methodological guidelines, with advice from expert consultants for each topic. The bulletins are subject to extensive and rigorous peer review.

Effectiveness Matters

  Effectiveness Matters provides updates on the effectiveness of important health interventions for practitioners and decision makers in the NHS. Topics covered to date include Aspirin and Myocardial Infarction, Helicobacter Pylori and Peptic Ulcer, Influenza Vaccination and Older People and Screening for Prostate Cancer. Screening for Prostate Cancer is accompanied by a patient information leaflet Screening for Prostate Cancer: The Evidence. Information for Men Considering or Asking for PSA tests. Effectiveness Matters is a free publication available on subscription. To subscribe to Effectiveness Matters or to order CRD Reports, contact CRD Publications (Tel.) 01904 433648.


  Quarterly newsletter publications funded as a pilot scheme by the Welsh National Board for nursing, midwifery and health visiting educationalists.

Evidence Based Emergency Medicine Home Page

  A group of physicians at Lincoln Hospital with a commitment to Evidence Based emergency medicine have created a Web site containing a CAT-Bank, Journal Club and support materials on how to Formulate a Question, Appraise a Study and search the literature.

Evidence Based Health Care

  Formerly known as Evidence-Based Health Policy and Management the principal purpose of the journal of Evidence-Based Health Care is to provide managers with the best evidence available about the financing, organisation and delivery of health care. Appraisal criteria for different types of study design are available from this site.

Evidence Based Healthcare Links Pages

  A ScHARR Compilation page of sites with a good coverage of links to Evidence Based Healthcare resources.

Evidence Based Healthcare - a resource pack

  This pack contains reading and key references concerning the background and current thinking on evidence-based health care and details of the groups and organisations involved in this movement. The pack is designed to guide your reading around the subject and to aid contact with national organisations and academic bodies that are playing a role in promoting and enabling evidence-based health care.

Evidence Based Medicine

  A journal formed by the BMJ Publishing Group with the American College of Physicians to help clinicians base decisions on the best current scientific evidence.

Evidence Based Medicine Course

  Online tutorial prepared by a Reference Librarian and HTML Programmer at State University of New York. Topics covered include: Purposes of Evidence Based Medicine, A Guide to Research Methods, Searching Biomedical Databases, Applying EBM to Online Searching and Evaluating the Studies You Find.

Evidence Based Medicine

  The purpose of the secondary journal, Evidence-Based Medicine, is to alert clinicians to important advances in internal medicine, general and family practice, surgery, psychiatry, paediatrics, and obstetrics and gynaecology by selecting from the biomedical literature those original and review articles whose results are most likely to be both true and useful. These articles are summarised in value-added abstracts and commented on by clinical experts.

Evidence-Based Medicine - Edizione Italiana

  The site for the Italian language edition of the Evidence Based Medicine journal (see above). Contents pages are available for 1997 onwards together with the full text of some of the articles.

Evidence Based Medicine : Principles and Practice

  Produced by Dr. P. Badrinath, Asst. Professor & Epidemiologist, Dept. of Community Medicine, United Arab Emirates University this presentation contains a useful powerpoint package of slides plus a series of "tasks" suitable for getting people started in EBM.

Evidence-Based Medicine in Japan
(Japanese Language)
Based at the Department of Public Health of the University of Nihon. Set your browser for Japanese characters.

Evidence-Based Medicine in Switzerland

  (German Language) A journal club and EBM site in German maintained by Johann Steurer.

Evidence-Based Medicine in Taiwan

   (Chinese Languag) An introduction to Evidence-Based Medicine in Chinese (set up your browser to accept Chinese characters!).

Evidence Based Medicine Resource List

  This site maintained by Chris Cox at the Library at the University of Hertfordshire has useful references and links to other resources. Although lacking the comprehensiveness of the ScHARR Guide to Evidence Based Practice this site more than makes up for this with its conciseness and clarity. Probably the best single compilation page on EBM on the Web.

Evidence-Based Medicine Reviews

  Ovid's Evidence-Based Medicine Reviews (EBMR) is a database designed for use by clinicians, researchers and students. Reflecting the current practice in medicine to base clinical decisions on accumulated evidence from the primary medical literature, Evidence-Based Medicine Reviews provides content from two premier sources: the Cochrane Library and Best Evidence.

Evidence Based Medicine Training Packages

  This is a ScHARR list of Teaching Packages and resources found on the World Wide Web. It includes both self-directed learning and tools to support teaching sessions.

Evidence Based Medicine Workbook : Critical appraisal for clinical problem solving

  The home page for the workbook published by Butterworth Heinemann, currently being translated into Spanish and Japanese. The site-owner has plans to develop the Web pages in the near future.

Evidence Based Mental Health

  The Web site for the sister journal to Evidence-Based Medicine contains the following: Full-text of the EBMH notebook; Full-text of selected articles; Archive of previous issues; Overview of journal purpose and policy; Glossary of terms and Letters and debate section.

Evidence Based Nursing

  The first issue of this sibling journal to Evidence Based Medicine and Evidence Based Mental health was published in November 1997 by the BMJ Publishing Group.

Evidence Based On Call

  A team of clinicians at the Centre for Evidence-Based Medicine in Oxford, England has set up "Evidence-Based On-Call" to meet the challenge of providing clinically relevant evidence-based advice at the bedside. EBOC will produce practical advice on common on-call problems by using the best evidence available to create easy-to-use guidelines using high-quality techniques to search the literature for the best journal articles on specific on-call problems. EBOC has developed an internet authoring tool allowing clinicians with EBM experience to create one-page summaries of these articles. These summaries, known as critically-appraised topics or CATs, will be added to a central electronic database and used to create clinical guidelines. A panel of clinical experts will review each guide before it is published in print, on CD-ROM and on the internet. The Oxford team will monitor the literature and update CATs and guides regularly.

Evidence Based Pathology

  This site, developing at the University of Nottingham, is currently a gateway to resources on EBM. However it is likely to develop into a valuable resource in its own right.

Evidence Based Pediatrics

  A resource for evidence based paediatrics at the University of Michigan containing Critically Appraised Topics,|Guidelines for a Journal Club | CAT Template available as a MS Word document.

Evidence-Based Practice Centers

  The Agency for Health Care Policy and Research (ahrq) established 12 centers in the United States to develop
evidence reports and technology assessments of diagnostic and therapeutic interventions used in a variety of clinical
conditions. The ahrq has chosen to pursue a partnering approach that brings developers and users together at the
beginning of the process. These partners, which may be professional societies, health plans, states, and other entities, will
use the products of the Evidence­based Practice Centers (EPCs) to develop and implement practice guidelines and other
clinical quality improvement tools.

Evidence Based Purchasing

  Evidence-Based Purchasing is a bimonthly digest of evidence about effective care and is intended to support the commissioning role. It is a selection of material received, commissioned, or found in journals by South and West R&D Directorate. A subject index is also available.

Evidence Based Topics

  A list of EBM topics organised alphabetically by Medical subject heading with hypertext links to the relevant WWW page. Amongst the sources covered are Bandolier, some of the EBM journal clubs on the internet, the ahrq and US and Canadian Preventative Task Force Guidelines. Now you can follow up your MEDLINE search by looking at the appropriate MeSH heading in this very useful list.

Evidence-supported Medical Union (EMU)

  Evidence-supported Medicine Union (EMU) is funded through the West Midlands Regional Levy Board to promote evidence based health care for the NHS in the West Midlands.

Evidências para Melhores Decisões Clínicas

  A Portugese language Web-based version hosted by the Brazilian Cochrane Centre of a printed booklet that acts as an introduction to Evidence Based Medicine.

Filtering the literature

  This ScHARR Compilation page lists a number of sites that use the methodological filters developed by McMaster University and others for retrieving methodologically sound articles from bibliographic databases.

Finding the literature

  This ScHARR Compilation page provides a list of a number of sites that give guidance on searching for the evidence.

Framework for Appropriate Care Throughout Sheffield (FACTS) Project

  This is a city-wide project based in Sheffield aimed at implementing change in primary care. Initial efforts have been aimed at getting aspirin to heart disease patients in Sheffield.

A Gathering of Evidence [Newsletter]

  A Gathering of Evidence is published periodically by Group Health Northwest. It summarises clinical articles based on rigourous research from major biomedical journals. Abstracts of articles are prepared to provide practitioners with the information they need to review the type of study, the population studied, the methods used, and the key results of the study. Commentary by a physician affiliated with Group Health Northwest accompanies the abstract, as well as suggested evidence-based medicine resources.The same organisation produces what it claims are evidence based guidelines. Topics covered to date include Use of x-rays to evaluate ankle and foot injuries in adults (The Ottawa Ankle Rules), Measuring Prostate Specific Antigen (PSA) to screen for prostate cancer, Neuroanatomic Imaging in Patients with Acute Low Back Pain, Surgery in Patients with herniated Lumbar Disc and the Use of Antenatal Corticosteroids in Pregnant Women at Risk of Preterm Delivery.

Centre for Evidence Based Mental Health Glossary of Terms

Clinical Epidemiology & Evidence-Based Medicine Glossary

Clinical Epidemiology Definitions

Evidence-Based Medicine Glossary

Evidence Based Medicine Glossary

Evidence Based Medicine Journal Glossary

GIMBE - Gruppo Italiano per la Medicina Basata sulle Evidenze Probably the best non-English Language EBM site on the Web this new resource contains definitions on the various stages of EBM, a comprehensive bibliography and an excellent links page.


  Guideline is a UK-based initiative to develop an electronic database of critically-appraised, clinical practice guidelines for health and allied care professionals across the National Health Service (NHS). The project began in March 1997 and is funded by the four health authorities of Oxfordshire, Berkshire, Buckinghamshire and Northamptonshire until August 1998.


  This is a listing of a number of guidelines available in full-text from the WWW.

Health Evidence Bulletins, Wales

  The Health Evidence Bulletins - Wales are a new initiative in the field of health information since they act as signposts to the best current evidence across a broad range of evidence types and subject areas. Where information from randomised controlled trials is available it is included. However, many health issues do not lend themselves easily to investigation, or have not yet been studied, by this method.

Health Reviews for Primary Care Providers

  A listing of documents about primary care medicine and medical practice, available through the World Wide Web. Some links are to the documents themselves. Others are to article reviews, plus links to the articles' abstracts, when available.The documents were selected to serve the information needs of primary care practitioners.

Health Technology Assessment (HTA) Database

  The HTA Database, mounted by the NHS Centre for Reviews and Dissemination at the University of York, contains abstracts produced by INAHTA (International Network of Agencies for Health Technology Assessment) and other healthcare technology agencies.

Health Technology Assessment Reports

  This resource at the Wessex Institute for Research and Development contains abstracts for the completed reviews from the National Health Service Health Technology Assessment Programme.

Health Technology Assessment Resources

  This ScHARR compilation page lists the primary international sites involved in Health Technology Assessment activities.


  An EBM collaborative effort between the Library of the Health Sciences-Peoria, University of Illinois at Chicago, (LHS-Peoria) , the National Network/Libraries of Medicine Greater Midwest Region and the Committee on Institutional Cooperation's (CIC) HealthWeb Project.

HIRU - The Health Informatics Research Unit, at McMaster University's Department of Clinical Epidemiology and Biostatistics in Canada, featuring a large inventory of evidence based resources and an on-line database.

Implementation and Change in the Health Service

  A sub-site of the Turning Research Into Practice (TRIP) initiative, this resource summarises between 5-10 articles on changing clinical practice each month. It also includes other useful Internet links on implementation and change.

Institute for Clinical Evaluative Sciences

  The Institute for Clinical Evaluative Sciences in Ontario (ICES) is a non-profit research organization dedicated to conducting research that contributes to the effectiveness, quality and efficiency of health care in the province of Ontario. It produces the newsletter informed for physicians.

InfoRetriever: Evidence for the Point of Care

  Software to bring evidence-based information to the point-of-care. InfoRetriever is software that claims to provide key resources for primary care physicians in a highly portable, fully indexed format on the Newton MP2000/2100 or E-Mate series of handheld computers. A demo may be downloaded from their site. InfoRetriever includes: over 260 abstracts from the Cochrane Database of Systematic Reviews, with over 100 new reviews added annually, over 240 critical appraisals from the Journal of Family Practice POEMs feature, with 96 more added annually, a diagnostic test calculator (sensitivity, specificity, likelihood ratios, and post-test probabilities for over 200 common tests), a history and physical exam compendium, evidence tables and summaries from key evidence-based treatment guidelines (ahrq, USPSTF, others), useful clinical prediction rules for important conditions like chest pain, sore throat, and pneumonia. The producers plan to provide updates at least every 3 months, synchronized with the release of the quarterly update to the Cochrane Library. Each update will include new Cochrane Library abstracts, JFP POEMs, and new diagnostic test data.

Information Mastery: An Introduction

  A Web-based course from Michigan State University that introduces the basic concepts of Information Mastery, Evidence-Based Medicine (EBP), and critical appraisal of the medical literature. Contents include:Reading an article about diagnosis, Reading an article about therapy, Reading an article about prognosis and Reading an overview or meta-analysis


  Attractively packaged site regarding pediatric intensive care. Includes a comprehensive and concise bibliography of EBM resources on the Web, maintained by Adrienne Randolph.


  InterDEC is a collaboration of organisations which have been established to provide commissioners in health authorities and primary care groups and NHS Trusts with research knowledge about the effectiveness and cost-effectiveness of acute service interventions. Members include: Development and Evaluation Service at The Wessex Institute for Health Research and Development, which supports the South and West Development and Evaluation Committee (DEC); The Working Group for Acute Purchasing of The Trent Institute for Health Services Research/School of Health and Related Research (ScHARR); The Development and Evaluation Service team at the Department of Public Health and Epidemiology, University of Birmingham; and the Scottish Health Purchasing Information Centre (SHPIC).

The Joanna Briggs Institute For Evidence Based Nursing & Midwifery

  A key function of the Joanna Briggs Institute is to disseminate Best Practice Information via summary sheets. These are widely distributed and are also available electronically in this Web site (requires Adobe Acrobat Reader).

Journal Club on the Web

  This Web site is an experiment in implementing an on-line, interactive general medical "journal club" which periodically summarizes and critiques articles from the recent medical literature and collects and posts readers' comments. The articles are primarily in the field of adult internal medicine, and mainly from the NEJM, Annals of Internal Medicine, JAMA and the Lancet.

Journal of Family Practice POEMs (Patient Oriented Evidence that Matters)

  The POEMs feature is designed to support the evidence-based practice of medicine. Each month, they review over 80 journals to identify the 8 articles with patient-oriented outcomes that have the greatest potential to change the way primary care clinicians practice. These articles are then critically appraised by expert family physicians, educators, and/or pharmacologists.


  This online edition of JSCAN contains the full text of Journals Scan, a monthly publication. This site also contains some other resources which is unique to the Website. Access to the entire site is free as on now. Journal Scan aims to keep you updated on the recent developments in the fields of Medicine & Health.  JSCAN contains articles from journals that provide evidence for treatment, diagnosis or prognosis. These  are presented in a question and answer format. JSCAN is compiled and edited by  Dr.P.Badrinath & Prof. Owen Lloyd, Department of Community Medicine, Faculty of Medicine & Health Sciences, United Arab Emirates University.

Literature Searching

  This ScHARR Compilation page lists those sites judged to be of value in learning how to search for the evidence.

MD Digests

  This feature of the Physician's Page of the Silverplatter information resource includes clinical questions answered from a recent article of literature and supported by a selective bibliography.

Medical SmartSearch

  Medical SmartSearch is a single gateway that attempts to provide references to answer clinical questions around diagnosis, aetiology, prognosis and therapy (plus physical findings, adverse treatment effects and screening/prevention) by searching only high-quality sources. Smartsearch always searches: 1. Merck Manual| MEDLINE for review articles and editorials that have full texts available |National Guideline Clearinghouse from the Agency for Health Care Policy and Research |Database of Abstract of Reviews of Effectiveness (DARE)| MEDLINE for original research.
Depending of the focus requested SmartSearch will search PubMed with the highest sensitivity filters developed by Haynes et al.

Medicina basada en pruebas : Evidence Based Medicine (EBM)

  An excellent Spanish-Language resource that not only contains links to other sites but includes transaltions of key items for Evidence Based Medicine (e.g. journal articles and the Netting the Evidence resource guide).

Méta-analyses des essais thérapeutiques (French)

  Ce site propose une série de ressources relatives aux méta-analyses des essais thérapeutiques. [A valuable bibliographic site with many English Language references].

MRC Clinical Trials Website

  The Medical Research Council (UK) Clinical Trials Web site includes the MRC's role in trials, how to apply for funding,
guidelines on good clinical practice in trials and a directory of current trials.

National Guideline Clearinghouse (U.S.)

  The National Guideline Clearinghouse (NGC) is a comprehensive database of evidence-based clinical practice guidelines and related documents produced by the Agency for Health Care Policy and Research (ahrq), in partnership with the American Medical Association (AMA) and the American Association of Health Plans (AAHP). The NGC mission is to provide physicians, nurses, and other health professionals, health care providers, health plans, integrated delivery systems, purchasers and others an accessible mechanism for obtaining objective, detailed information on clinical practice guidelines and to further their dissemination, implementation and use. Key components of NGC include: Structured abstracts (summaries) about the guideline and its development; a utility for comparing attributes of two or more guidelines in a side-by-side comparison; syntheses of guidelines covering similar topics, highlighting areas of similarity and difference; links to full-text guidelines, where available, and/or ordering information for print copies; an electronic forum for exchanging information on clinical practice guidelines, their development, implementation and use; annotated bibliographies on guideline development methodology, implementation, and use.

National Institute for Clinical Excellence

  The National Institute for Clinical Excellence (the Institute) is a Special Health Authority which will work with the NHS, the Institute will systematically appraise health interventions. It will offer clinicians and managers clear guidance on which treatments work best for patients and which do not. This guidance will support everyone in the NHS including doctors, nurses, midwives and other health professionals - those who make the complex decisions about the treatment of individual patients. Guidance will also be available for patients and the public.

National Library of Medicine's Health Services/Technology Assessment Text (HSTAT)

  This WWW resource contains the following collections: ahrq Supported Guidelines, ahrq Technology Assessments and Reviews, ATIS (HIV/AIDS Technical Information), NIH Warren G. Magnuson Clinical Research Studies, NIH Consensus Development Program, PHS Guide to Clinical Preventive Services (1989) and SAMHSA/CSAT Treatment Improvement Protocol (TIP).

National Pathways Association

  The National Pathways Association (NPA) exists to promote the development and use of Pathways nationally. It was formed in the early 1990's out of the local networks of Pathway Users around the UK. As the organisation has grown, the membership has expanded across the many organisations and individuals who are interested in the development and use of Pathways. The group is multi-disciplinary and multi-professional, and includes healthcare individuals across the independent, private and public sectors. The NPA has an advisory role to central government and is a key player in the development and promotion of the new quality agenda. The NPA Website is open to both NPA members and non-members. However, access to certain pages is restricted by password to members only.

North Thames Research Appraisal Group

  The North Thames Research Appraisal Group is an education and training consultancy consisting of a mixed group of 35 researchers, academics, clinicians and other healthcare professionals interested in promoting evidence-based healthcare (EBHC). The means by which they achieve this goal is through the design and delivery of a wide range of critical appraisal skills workshops and related activities. In addition to delivering an annual programme, of some 40+ critical appraisal skills workshops covering 9 topic areas, NTRAG staff and tutors also work withTrusts, Health Authorities and other NHS organisations around the country to create short-course programmes tailored specifically to local requirements. These activities are generally delivered on-site, enabling educational content to be linked directly to local patient and service-delivery priorities.

Numbers Needed to Treat

  This is a ScHARR Compilation page containing links to NNT sites, tools and a Medline Bibliography.

Occupational Therapy Evidence Based Practice Research Group

  The McMaster Occupational Therapy Evidence-based Practice group focuses on research to critically review evidence regarding the effectiveness of occupational therapy interventions and to develop tools for evaluation of occupational therapy programmes. They have produced review forms and guidelines for quantitative and qualitative articles, available to download in Acrobat pdf format

Office of Technology Assessment

  Although the remit of the U.S. based Office of Technology Assessment is much broader than just healthcare they do produce a number of useful reports; including the report "Identifying Health Technologies that Work". The full text of their reports is available from this site.

Online listing of Clinical Trials Registers

  An online version of the listing of Clinical Trials Registers maintained by the New England Cochrane Center, Providence office since 1988.

Oxford & Anglia Mental Health Web (OXAMWEB)

  To help support evidence-based practice, the Directorate of Research and Development for the Anglia and Oxford Region has provided resources for Internet connection in libraries in the Region and for the development of OXAMWEB. To be included in OXAMWEB, articles must fulfil the following minimum criteria written in English, free to view, easy to understand and clearly presented, likely to be relevant and helpful to site users/ patients/ professionals. An important part of the material, marked with an EB (evidence-based) logo, also fulfils the more stringent criteria of Evidence Based Medicine.

Pediatric Evidence Based Medicine Homepage

  This Web page is part of a comprehensive program to improve the use of Evidence Based Medicine in the care of children. This program will consist of a research and demonstration site at the University of Washington School of Medicine, education of pediatric practitioners, creation of an infrastructure for pediatric EBM, conduct of systematic reviews, and an interface with the Cochrane Collaboration. The site includes Critically Appraised Topics current summary of information on pediatric-related issues; Diagnostic Tests (Sensitivities, specificities, likelihood ratios, and predictive values of diagnostic tests); Emergency Room Diagnoses.

PEDro - Physiotherapy Evidence Database

  PEDro, an initiative of the Centre for Evidence-Based Physiotherapy (CEBP). PEDro is the Physiotherapy Evidence Database. It has been developed to give physiotherapists and others rapid access to bibliographic details and abstracts of randomised controlled trials in physiotherapy. Most trials on the database have been rated for quality to help to quickly discriminate between trials which are likely to be valid and interpretable and those which are not.

PedsCCM Evidence-Based Journal Club

  This site reviews clinical trials relevant to paediatric care.

Percentage of Evidence Based Treatment

  This is a ScHARR compilation page of studies (and email discussions) concerning the percentage of evidence based healthcare in various specialties. It traces the pre-history of the debate and then, following the landmark study by Ellis et al, 1995, it documents all contributions to the debate.

Primary Care Sharing the Evidence (PRISE)

  The PRISE (Primary Care Sharing the Evidence) project is part of the libraries and librarian development programme managed by the Health Care Libraries Unit and supported by the Anglia and Oxford R&D Directorate. PRISE is a two year project which aims to provide timely access to high quality evidence for GP's and other practice-based professionals. The project focuses on twelve Primary Health care sites, including one dental practice and two GP practices in each of the four counties of the former Oxford Health Authority Region.

Promoting Action on Clinical Effectiveness (PACE)

  This initiative, run from the King's Fund in London, works through a network and sixteen demonstration projects to achieve clinical change for effective healthcare. A progress report is available from their site.

PsyBECA: (Spanish)

  PsyBECA is a non-profit making Spanish-Language site aimed at making available the most current rigorous research in Psychiatry.

R&D Strategy pages

  Most of these pages deal with the mechanics of the strategy but many practitioners will be interested in research per se and will want to keep up to date with the NHS strategy. There are now several home pages.

RAND Corporation

  RAND is a US-based nonprofit institution that aims to improve public policy through research and analysis. RAND aims to carry out high-quality, objective research addressing problems of domestic policy including health care. RAND has been studying health care issues for more than thirty years. Today, RAND conducts one of the largest private, nonprofit programs of health policy research and analysis in the world. They publish numerous reports and other documents in areas of health care technology assessment.

Resources for Evidence Based Surgery

  A site, created for all surgeons and the related medical community, hosted by the Royal College of Surgeons, England. It contains a listing of the 300+ journal titles held by the Library together with links to journal home pages ( in many cases, providing current content pages, full text articles, etc). Similar links to the most frequently used journals in the different categories of surgery (based on the Science Citation Index). Links to free medical databases including Medline and a listing of Cochrane Systematic Reviews relevant to surgery are also available together with details of guidelines and reports publicsed by the RCS and other surgical bodies/societies. Links to internet resources relevant to evidence based surgery complete the picture together with details of the many email discussion groups open to surgeons.

Resources for Practicing EBM

  This site specialises in paediatric critical care (aka intensive care) medicine but many of its links are of wider applicability to EBM.


  REVMAN is the Cochrane Collaboration's own systematic review software for producing Cochrane-type reviews. Technical support is only provided to the members of the Cochrane Collaboration but the software is freely available from the UK Cochrane Centre's ftp site.

Screening and Diagnostic Tests (Cochrane Collaboration)

  The Cochrane Collaboration Methods Working Group on Screening and Diagnostic Tests has placed its recommendations on how to search for, appraise and pool results of studies of diagnostic accuracy on the Web. The document includes a methodological bibliography.

School of Health and Related Research(ScHARR), University of Sheffield
School of Health And Related Research (ScHARR) This health services research department within the University of Sheffield is involved in finding the evidence (expertise in literature searching); appraising the evidence (critical appraisal training) and producing the evidence (systematic reviews). The Information Resources Section of ScHARR produces a bibliography and resource guide entitled "The ScHARR Guide to Evidence Based Practice".

ScHARR-Lock's Guide to the Evidence

  This is a guide to printed sources of evidence arranged by Medical Subject Heading (MeSH). It focuses on grey literature from UK academic and quasi-governmental sources and aims to complement Michael Zack's list of Evidence-based Topics.

Scottish Health Purchasing Information Centre (SHPIC)

  SHPIC was set up by the NHS Management Executive to carry out effectiveness and cost benefit studies on health service interventions, and to produce concise reports for purchasers. The full text of their current publications is available from this site.

Scottish Intercollegiate Guidelines Network (SIGN)

  The Scottish Intercollegiate Guidelines Network (SIGN) develops and publishes evidence-based clinical practice guidelines for use by the health service in Scotland. Full text of many of their guidelines is available from their site. You will however require an Acrobat Reader.

Searching the Internet for information to support clinical decisions

  A Web page produced by Dalhousie University Continuing Medical Education and The Medical Society of Nova Scotia to support a workshop on how the Internet can be used for clinical decision support. Several scenarios are given together with suggested resources.

Seeking the Evidence : a protocol

  This evidence seeking protocol, developed by Andrew Booth at ScHARR, outlines the stages by which evidence can be accumulated for Evidence Based digests such as those found in Journal of Clinical Excellence. ScHARR Information Resources is the majority contributor for digests published in this journal.

Stiftung Paracelsus heute in Switzerland

  (German Language) A critical appraisal of diagnostic, therapeutic and preventive interventions of modern as well as unconventional medicine, plus courses, symposia and research using EBM techniques.

Sources of Evidence (CASPFEW)

  A guide to some of the publications, databases, Web resources and organisations that may be useful in helping you to locate evidence-based health care information, compiled by librarians in the Health Libraries and Information Network (HeLIN) in the Anglia & Oxford Region and the CASP team. The guide is not an attempt at a comprehensive list, but does hopefully point towards the main sources of evidence that exist in this area at present.

South and West R&D Briefing Papers

  The Briefing Papers Series commissioned by the R&D directorate offers brief but authorative discussions on the effectiveness of health interventions.


  SumSearch is a meta-search engine that searches: 1.the Merck Manual, 2.MEDLINE for review articles and editorials from high quality, general journals that have full texts available, 3.National Guideline Clearinghouse from the Agency for Health Care Policy and Research (ahrq), 4.Database of Abstract of Reviews of Effectiveness (DARE) and 5.MEDLINE for original research.

SUNY Health Sciences Evidence Based Medicine Course

  An online tutorial providing a comprehensive overview of Evidence Based Medicine.

Swedish Council on Technology Assessment in Health Care (SBU)

  SBU's task is to evaluate methods used within health care and to look critically at their costs, their risks and their benefits. SBU assesses the medical, ethical, social and economic impact of new and established medical procedures.

Systematic Literature Review Training Module

  This module at the University of Leeds has been designed to provide a basic introduction to the systematic literature review process. It follows the NHS CRD Guidelines for systematic reviews and includes a self assessment questionnaire for evaluating learning outcomes.

Systematic Reviews Training Unit

  A joint initiative of the Institute of Child Health, the Royal Free Hospital School of Medicine and University College London. The Unit, set up in April 1996, aims to train health professionals in the conduct of systematic reviews of research evidence and to produce rigorous reviews which will support efficient practice and policy in the health service.

Trent Working Group on Acute Purchasing

  The Trent Working Group on Acute Purchasing was set up to enable purchasers to share research knowledge about the effectiveness and cost-effectiveness of acute service interventions and determine collectively their purchasing policy. The Group is facilitated by The School of Health and Related Research (ScHARR), part of the Trent Institute for Health Services Research. A list of work in progress and current publications is available at this site.

Turning Research Into Practice (TRIP) Database

  This resource, hosted by the Centre for Research Support in Wales, aims to support those working in primary care.The database has 8000 links covering resources at 28 different centres and allows both boolean searching (AND, OR, NOT) and truncation.

UK Clearing House on Health Outcomes, including an Outcomes Database of Structured Abstracts

  The UK Clearing House on Health Outcomes, based within the Nuffield Institute for Health at the University of Leeds, aims: to develop approaches to outcomes assessment within routine health care practice and to promote the role of health outcomes within decision making in health care commissioning and provision.

Ulmer Initiative für Evidence-Based Medicine

  (German Language) EBM sitewith areas under construction. The site does contain links to papers, information for students, etc.

Unit for Evidence Based Practice and Policy (UEBPP)

  The UEBPP is a 'virtual' subunit of the Joint Department of Primary Care and Population Sciences (PCPS) of the merged medical schools of University College London and the Royal Free Hospital. Their Web page is maintained by Dr Trisha Greenhalgh, and describes the work of a number of key staff at PCPS who undertake work in evidence-based health.

US Prevention Task Forces Guides to Clinical Preventive Services

  In-depth guidelines on screening and counseling for a viariety of common conditions.

Users' Guides to the Health Care Literature

  The Evidence Based Medicine Working Group, a group of clinicians at McMaster and colleagues across North America, have created a set of guides, published in the Journal of the American Medical Association (JAMA). The Users' Guide series aim to assist clinicians to keep up to date in their clinical discipline and to find the best way to manage a particular clinical problem. The User's Guides put much emphasis on integrative studies, including systematic overviews, practice guidelines, decision analysis, and economic analysis. They introduce strategies for efficiently searching the medical literature. Full-text of some of the Guides is available.


  WebDoc is an ongoing program to design and test online publication formats for biomedical knowledge. The first WebDoc design, the clinical extract, is tailored to help physicians choose relevant articles for clinical problem solving. The clinical extract's design highlights information in the article that is most relevant to patient care, and simplifies access to the contents for problem solving.

Wessex Institute for Health Research and Development

  The Wessex Institute aims to provide the highest quality research and intelligence, education and training and innovation and development services. It aims to help the NHS to secure the strongest possible knowledge base for improving the health of the population.

WISDOM Project

  WISDOM is a pilot project based at the University of Sheffield and funded by the National Health Service Executive to create an on-line environment, using the Internet to train primary care professionals in informatics. At the heart of the project is a discussion group: this Web site supports the group and offers information resources and background to the project. Evidence Based Practice is one of the focus areas for the project (Practice because it targets all members of the Primary Health Care Team). Several tutorials, originally distributed by e-mail but now deposited in the project archive, cover aspects of evidence based practice.

Workshop on How to Teach Evidence Based Clinical Practice

  McMaster University Department of Clinical Epidemiology and Biostatistics have assembled sets of readings dealing with evidence-based medicine and critical appraisal issues in therapy, diagnosis, prognosis, harm, overviews and economic analysis. Some materials, complete with checklists and cribsheets is available on the Internet, and may be downloaded to support Critical Appraisal skills programmes locally.

Zack's Guide

  An excellent assembly of relevant sites, and includes a massive list of EBM documents on the Web, and it's useful even though the author (Michael Zack) no longer maintains it.


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