In today's Vidyya, we bring you an updated report on inahalants. Inhalants are volatile substances that produce chemical vapors that can be inhaled to induce a psychoactive, or mind-altering, effect. Although other abused substances can be inhaled, the term "inhalants" is used to describe a variety of substances whose main common characteristic is that they are rarely, if ever, taken by any route other than inhalation. The general public is often naive about the uses and abuses of possible inhalants. This in-depth report can education patients and practitioners alike and was sactioned by the National Institute On Drug Abuse.
In FDA approvals, the FDA has issued an accelerated approval for Kaletra, a protease inhibitor, for adults and children greater than 6 months of age with HIV. Kaletra is a combination of lopinavir and ritonavir, (a previously approved protease inhibitor). Lopinavir's antiviral properties are combined with a low dose of ritonavir that inhibits lopinavir's metabolism. This results in blood levels of lopinavir that enhance its effectiveness against HIV. The combination drug will be available within a few weeks.
On 7 September 2000, the CDC was notified by Idaho Department of Health about a case of acute febrile illness in a 35-year-old man; the illness was characterized by acute onset of high fever, chills, headache, and myalgias. The patient had participated in the EcoChallenge Sabah 2000 Expedition Race, a multisport event held during August 20-September 3, at various sites in Sabah in Malaysian Borneo. The man and at least 50 others have been tentatively diagnosed with leptospirosis. Leptospirosis has been blamed for several deaths in Thailand this year and is being carefully watched by the World Health Organization.
For your information, Vidyya is providing some technical information on Leptospirosis. Leptospirosis symptoms include fever, headache, chills, muscle aches, vomiting, jaundice, anemia, and sometimes a rash. The incubation period usually is 10 days, with a range of 4-19 days. If not treated, the patient could develop kidney damage, meningitis, liver failure, and respiratory distress. In rare cases, death occurs.
Finally, in a story we've been watching for aobut a month. Wyeth-Ayerst, the maker of Norplant said last week that it cannot guarantee that certain batches of the birth-control implants are effective. As a result of the questions regarding the efficacy of the implant, the company has announced it will reimburse some women for the costs of backup birth control.
The articles in today's Vidyya are:
As always, we hope you enjoy the issue.