Vidyya Medical News Servicesm
Vidyya, from the Sanskrit "vaidya," a practitioner who has come to understand the science of life.

Volume 1 Published - 14:00 UTC    08:00 EST    31-October-2000      
Issue 201 Next Update - 14:00 UTC 08:00 EST    01-November-2000      

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Vidyya Medical News Service For 31-October-2000:

Fertility researchers at the National Institute of Child Health and Human Development (NICHD) have found that a gene in female mice is essential for their egg cells to later develop beyond the two-cell stage after fertilization. This finding could lead to new insights into the causes of unexplained infertility in women. The finding may also provide an important lead for developmental biologists studying how an organism progresses from a single cell to a complex organism.

Respiratory infections strike millions of people each year and collectively cause more deaths than any single infectious disease. For the first time, scientists have determined the structure of a key protein from a paramyxovirus, a leading cause of respiratory disease in children throughout the world.

In a new study, Vioxx® 25 mg (rofecoxib), the prescription osteoarthritis medicine developed and marketed by Merck & Co., Inc., reduced osteoarthritis pain at night and at rest to a greater degree than celecoxib 200 mg and acetaminophen 4,000 mg. Results of the study were reported yesterday at the annual meeting of the European League Against Rheumatism, the largest rheumatology conference in Europe.

In an separate analysis also presented at the European League Against Rheumatism (EULAR), the renal safety profile of Vioxx(R) (rofecoxib) was not statistically different from celecoxib. In a separate analysis, Vioxx had a renal safety profile that is similar to that of certain non-steroidal anti-inflammatory drugs (NSAIDs), Merck & Co., Inc. confirmed today in response to a news release by a competitor.

Vioxx is a nonsteroidal anti-inflammatory drug that exhibits anti-inflammatory, analgesic, and antipyretic activities in animal models. The mechanism of action of Vioxx is believed to be due to inhibition of prostaglandin synthesis, via inhibition of cyclooxygenase-2 (COX-2). Get the prescribing information you need in today's issue of Vidyya.

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Editor: Susan K. Boyer, RN
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