Vidyya Medical News Service

Volume 3 Issue 198 Published - 14:00 UTC 08:00 EST 21-Oct-2001 Next Update - 14:00 UTC 08:00 EST 22-Oct-2001	Editor: Susan K. Boyer, RN © RAmEx Ars Medica, Inc. All rights reserved.

Information For Health Professionals: Cipro Dosing Chart

Infection*	Cipro^® Tablets^A	Cipro Oral Suspension^A,B,C	Cipro I.V.^D

Uncomplicated UTIs -acute uncomplicated -mild/moderate	250 mg bid for 3 days	5%—5 mL q12h 10%—2.5 mL q12h for 3 days
Uncomplicated UTIs -acute uncomplicated -mild/moderate	250 mg bid for 7 to 14 days	5%—5 mL q12h 10%—2.5 mL q12h for 7 to 14 days	200 mg q12h
Complicated UTIs -severe/complicated	500 mg bid for 7 to 14 days	5%—10 mL q12h 10%—5 mL q12h for 7 to 14 days	400 mg q12h
Chronic bacterial prostatitis -mild/moderate	500 mg bid for 28 days	5%—10 mL q12h 10%—5 mL q12h for 28 days	400 mg q12h
Urethral and cervical gonococcal infections -uncomplicated	250 mg single dose	5%—5 mL 10%—2.5 mL single dose

Acute sinusitis -mild/moderate	500 mg bid for 10 days	5%—10 mL q12h 10%—5 mL q12h for 10 days	400 mg q12h
Lower respiratory tract; Skin and skin structure -mild/moderate -severe/complicated	500 mg bid for 7 to 14 days	5%—10 mL q12h 10%—5 mL q12h for 7 to 14 days	400 mg q12h
	750 mg bid for 7 to 14 days	5%—15 mL q12h 10%—7.5 mL q12h for 7 to 14 days	400 mg q8h
Bone and joint -mild/moderate -severe/complicated	500 mg bid for >4 to 6 weeks	5%—10 mL q12h 10%—5 mL q12h for >4 to 6 weeks	400 mg q12h
Bone and joint -mild/moderate -severe/complicated	750 mg bid for >4 to 6 weeks	5%—15 mL q12h 10%—7.5 mL q12h for >4 to 6 weeks	400 mg q8h
Intra-abdominal (in combination with metronidazole) -complicated	500 mg bid for 7 to 14 days	5%—10 mL q12h 10%—5 mL q12h for 7 to 14 days	400 mg q12h
Infectious diarrhea -mild/moderate/severe	500 mg bid for 5 to 7 days	5%—10 mL q12h 10%—5 mL q12h for 5 to 7 days
Inhalational anthrax^E (post-exposure)	Adults: 500 mg bid for 60 days Children^F: 15 mg/kg bid not to exceed 500 mg per dose for 60 days	Adults: 5%—10 mL q12h 10%—5 mL q12h for 60 days Children^F: 15 mg/kg bid not to exceed 500 mg per dose for 60 days	Adults: 400 mg q12h Children^F: 10 mg/kg q12h not to exceed 400 mg per dose

^A Cipro Tablets and Cipro Oral Suspension may be taken with or without meals.
^B Cipro Oral Suspension must be reconstituted prior to administration. Cipro Oral Suspension should not be administered through a feeding tube.
^C One teaspoon (5 mL) of 5% Cipro Oral Suspension= one 250 mg Cipro Tablet.
One teaspoon (5 mL) of 10% Cipro Oral Suspension= one 500 mg Cipro Tablet.
^D Cipro I.V. should be administered by intravenous infusion over a period of 60 minutes. ^E Ciprofloxacin serum concentrations achieved in humans serve as a surrogate endpoint reasonably likely to predict clinical benefit and provide the basis for this indication.
^F The safety and effectiveness of Ciprofloxacin in children, adolescents less than 18 years of age, except for inhalational anthrax (post-exposure), pregnant women and lactating women have not been established.
*Due to susceptible strains of indicated organisms.
Please see prescribing information.

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