Vitamin C injections slow tumor growth in mice

Injecting high doses of vitamin C into mice with aggressive cancers slowed the growth of their tumors significantly without affecting normal tissues, researchers are reporting. While the potential anticancer effects of vitamin C (also known as ascorbate or ascorbic acid) have been studied for decades, the new findings provide "a firm basis" for advancing vitamin C as a pharmacologic agent for treating human cancer, they write in the August 5, 2008 Proceedings of the National Academy of Sciences. more  

Researchers discover how rheumatoid arthritis causes bone loss

Researchers have discovered key details of how rheumatoid arthritis (RA) destroys bone, according to a study published in the Aug. 22 edition of the Journal of Biological Chemistry. The findings are already guiding attempts to design new drugs to reverse RA-related bone loss and may also address more common forms of osteoporosis with a few adjustments. more

79 million US adults have medical bill problems or are paying off medical debt

The proportion of working-age Americans who have medical bill problems or who are paying off medical debt climbed from 34 percent to 41 percent between 2005 and 2007, bringing the total to 72 million, according to recent survey findings from The Commonwealth Fund. In addition, 7 million adults age 65 and over also had problems paying medical bills, for a total of 79 million adults with medical bill problems or medical debt. more  

Addiction treatment proves successful in animal weight loss study

Vigabatrin, a medication proposed as a potential treatment for drug addiction by scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory, also leads to rapid weight loss and reduced food intake according to a new animal study from the same research group. The study will be published online August 20, 2008, by the journal Synapse. Vigabatrin is currently undergoing U.S. Food and Drug Administration (FDA)-approved Phase II clinical trials against cocaine and methamphetamine addiction across the U.S. more

Breaking the 'mucus barrier' with a new drug delivery system  

Chemical engineers from Johns Hopkins University have broken the "mucus barrier," engineering the first drug-delivery particles capable of passing through human mucus — regarded by many as nearly impenetrable — and carrying medication that could treat a range of diseases. Those conditions include lung cancer, cervical cancer and cystic fibrosis, the research noted in a presentation scheduled for the 236th National Meeting of the American Chemical Society. more

LSUHSC research reports new method to protect brain cells from diseases like Alzheimer's 

New research led by Chu Chen, PhD, Associate Professor of Neuroscience at LSU Health Sciences Center New Orleans, provides evidence that one of the only naturally occurring fatty acids in the brain that has the ability to interact with the receptors originally identified as the targets of THC (the psychoactive component of marijuana) can help to protect brain cells from neurodegenerative diseases like Alzheimer's and Parkinson's. Published in the August 15, 2008 issue of the Journal of Biological Chemistry, the research focuses on the cellular and molecular mechanisms of inflammation, specifically the role these relatively recently discovered endogenous cannabinoids can play in the control of COX-2 and other cyclooxygenases. COX-2 is a key player in neuroinflammation and has been implicated in the development of neurodegenerative diseases and worsening of damage from such insults as traumatic brain injury and stroke. more

Primary care health consultations can be cost-effective and may help reduce cardiovascular risk

Offering health tests and health consultations in primary care settings can be cost-effective and may help in the fight against the increased burden of lifestyle diseases, according to new research published today in the Scandinavian Journal of Public Health (August issue published this week by SAGE). more

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