Cholesterol drug makes staph more vulnerable

An experimental cholesterol-fighting drug can also strip staph bacteria of their golden color and make the microbes more susceptible to killing by the immune system. The finding may lead to new options for battling Staphylococcus aureus bacteria, which are increasingly resistant to antibiotics. more  

Penn researchers identify first sex chromosome gene involved in meiosis and male infertility

A team of scientists led by University of Pennsylvania veterinary researchers have identified a gene, TEX11, located on the X chromosome, which when disrupted in mice renders the males sterile and reduces female fecundity. This is the first study of the genetic causes of infertility that links a particular sex chromosome meiosis-specific gene to sterility. more

UNC, Harvard develop inhaled TB vaccine

A new tuberculosis vaccine successfully tested at the University of North Carolina at Chapel Hill is easier to administer and store and just as effective as one commonly used worldwide. more  

FDA takes next step in establishing overseas presence agency on path to establish offices in China

In an important development, the U.S. Food and Drug Administration has received approval from the U.S. State Department to establish eight full time permanent FDA positions at U.S. diplomatic posts in the People's Republic of China, pending authorization from the Chinese government. more

Chart for professionals: Prescription drug abuse chart  

Medications can be effective when they are used properly, but some can be addictive and dangerous when misused. This chart provides a brief look at some prescribed medications that—when used in ways other than they are prescribed—have the potential for abuse and even addiction. more

Chart for professionals: Commonly abused drugs 

Schedule I and II drugs have a high potential for abuse. They require greater storage security and have a quota on manufacturing, among other restrictions. Schedule I drugs are available for research only and have no approved medical use; Schedule II drugs are available only by prescription (unrefillable) and require a form for ordering. Schedule III and IV drugs are available by prescription, may have five refills in 6 months, and may be ordered orally. Some Schedule V drugs are available over the counter. Download a chart in today's issue. more

Principles of drug addiction treatment: A research based guide

Drug addiction is a complex illness. It is characterized by compulsive, at times uncontrollable drug craving, seeking, and use that persist even in the face of extremely negative consequences. For many people, drug addiction becomes chronic, with relapses possible even after long periods of abstinence. The National Institute on Drug Abuse prepared this guide to help professionals deal with the problem of drug addiction. more

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