Volume 10 Issue 87
Published - 14:00 UTC 08:00 EST 27-Mar-2008 
Next Update - 14:00 UTC 08:00 EST 28-Mar-2008





Editor: Susan K. Boyer, RN
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Gene variant determines response to treatment for PCOS

NIH-sponsored researchers have discovered that women who have polycystic ovary syndrome (PCOS) are less likely to ovulate in response to a promising new drug treatment for the condition if they have a variation in a particular gene. more  

Cystic Fibrosis Foundation announces positive early results for phase 2 clinical trial of VX-770

The Cystic Fibrosis Foundation announced today that VX-770, an oral drug in development that targets a basic defect in CF, showed promising results in an ongoing Phase 2a clinical trial for patients who carry the G551D mutation of CF. The drug is being developed by Vertex Pharmaceuticals Incorporated. more

Folate scores a win in animal studies: Brief, high doses of B vitamin blunt damage from heart attack

Long known for its role in preventing anemia in expectant mothers and spinal birth defects in newborns, the B vitamin folate, found in leafy green vegetables, beans and nuts has now been shown to blunt the damaging effects of heart attack when given in short-term, high doses to test animals. more  

Umbilical cord blood cell therapy reduces pathology in animal model of Alzheimer's disease

Targeted immune suppression using human umbilical cord blood cells may improve the pathology associated with Alzheimer’s disease, a new study in a mouse model of this currently untreatable neurodegenerative condition reports. more

Heart failure treated ‘in the brain’  

Beta-blockers heal the heart via the brain when administered during heart failure, according to a new study by UCL (University College London). Up to now, it was thought that beta-blockers work directly on the heart, but the new study shows that the drugs may also act via the brain, suggesting that future therapies to treat cardiovascular disease could be targeting the central nervous system. more

Relaxation training may improve control of hard-to-treat systolic hypertension  

Adding the relaxation response, a stress-management approach, to other lifestyle interventions may significantly improve treatment of the type of hypertension most common in the elderly. Among participants in a study conducted at the Massachusetts General Hospital (MGH) Hypertension Program and the Benson-Henry Institute for Mind-Body Medicine at MGH, those who received relaxation response training in addition to advice on reducing lifestyle risk factors were more than twice as likely to successfully eliminate at least one blood pressure medication than were those receiving lifestyle counseling only. The study appears in the Journal of Alternative and Complementary Medicine. more

A ton of bitter melon produces sweet results for diabetes

Scientists have uncovered the therapeutic properties of bitter melon, a vegetable and traditional Chinese medicine, that make it a powerful treatment for Type 2 diabetes. more

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Women who have polycystic ovary syndrome (PCOS) are less likely to ovulate in response to a promising new drug treatment for the condition if they have a variation in a particular gene.