Tumor suppressor gene in flies may provide insights for human brain tumors
In the fruit fly's developing brain, stem cells called neuroblasts normally divide to create one self-renewing neuroblast and one cell that has a different fate. But neuroblast growth can sometimes spin out of control and become a brain tumor.
Major study highlights weight differences among 3-19 year-olds with type 1 and 2 diabetes
A major study of three to 19 year-olds has provided vital data on the weight problems faced by the growing number of children and young people with type 1 diabetes, which is more prevalent in younger age groups than type 2 diabetes. more
Statins can protect against Alzheimer's disease, according to new study
High cholesterol levels are considered to be a risk factor not only for cardiovascular disease including stroke, but also for the development of Alzheimer's disease. Therefore, many cholesterol lowering drugs, including statins, have been developed in recent years. In addition to the cholesterol reducing effect of statins Amalia Dolga, PhD, of the University of Groningen, The Netherlands, and her co-investigators have demonstrated that statins can protect nerve cells against damage which we know to occur in the brain of Alzheimer's disease patients. The results are published in the June issue of the Journal of Alzheimer's Disease. more
Caucasians are at higher risk of developing Ewing's sarcoma than other races
The largest analysis of its kind has found that Caucasians are much more likely than people in other racial/ethnic groups to develop a rare bone and soft tissue cancer called Ewing's sarcoma. In addition, among Caucasians with this cancer, men are more likely to die than women. Published in the August 1, 2009 issue of CANCER, a peer-reviewed journal of the American Cancer Society, the study indicates that examining the gender and racial differences related to Ewing's sarcoma could provide a better understanding of the disease and could lead to improved treatments for patients. more
The battle for CRTC2: How obesity increases the risk for diabetes
Obesity is probably the most important factor in the development of insulin resistance, but science's understanding of the chain of events is still spotty. Now, researchers at the Salk Institute for Biological Studies have filled in the gap and identified the missing link between the two. Their findings, to be published in the June 21, 2009 advance online edition of the journal Nature, explain how obesity sets the stage for diabetes and why thin people can become insulin-resistant.
Targeting helpers of heat shock proteins could help treat cancer, cardiovascular disease
Dissecting how heat shock protein 90 gets steroid receptors into shape to use hormones like estrogen and testosterone could lead to targeted therapies for hormone-driven cancers, such as breast and prostate, that need them as well, Medical College of Georgia researchers say. more
Adults with asthma not getting their flu shots
Because of increased risk of complications from influenza, vaccination of adults and children with asthma is recommended by the Advisory Committee on Immunization Practices. The Healthy People 2010 Objectives call for annual influenza vaccination of at least 60% of adults aged 18-64 years with asthma. However, Centers for Disease Control and Prevention (CDC) investigators have determined that the vaccination levels among asthma sufferers falls well short of this guideline. The results of their study are published in the August 2009 issue of the American Journal of Preventive Medicine. more
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