How amyloid beta reduces plasticity related to synaptic signaling
The early stages of Alzheimer's disease are thought to occur at the synapse, since synapse loss is associated with memory dysfunction. Evidence suggests that amyloid beta (Aß) plays an important role in early synaptic failure, but little has been understood about Aß's effect on the plasticity of dendritic spines.
New RNA interference technique can silence up to 5 genes
Researchers at MIT and Alnylam Pharmaceuticals report this week that they have successfully used RNA interference to turn off multiple genes in the livers of mice, an advance that could lead to new treatments for diseases of the liver and other organs. more
Exposure to tobacco smoke in childhood home associated with early emphysema in adulthood
Children regularly exposed to tobacco smoke at home were more likely to develop early emphysema in adulthood. This finding by researchers at Columbia University's Mailman School of Public Health suggests that the lungs may not recover completely from the effects of early-life exposures to tobacco smoke (ETS). The study is published in the December 2009 American Journal of Epidemiology. more
Johns Hopkins scientists discover a controller of brain circuitry
By combining a research technique that dates back 136 years with modern molecular genetics, a Johns Hopkins neuroscientist has been able to see how a mammal's brain shrewdly revisits and reuses the same molecular cues to control the complex design of its circuits. more
New research could advance research field critical to personalized medicine
It's the ultimate goal in the treatment of cancer: tailoring a person's therapy based on his or her genetic makeup. While a lofty goal, scientists are steadily moving forward, rapidly exploiting new technologies. Researchers at Georgetown Lombardi Comprehensive Cancer Center report a significant advance in this field of research using a new chip that looks for hundreds of mutations in dozen of genes.
Acupuncture reduces hot flashes, improves sex drive for breast cancer patients
Not only is acupuncture as effective as drug therapy at reducing hot flashes in breast cancer patients, it has the added benefit of potentially increasing a woman's sex drive and improving her sense of well-being, according to a Henry Ford Hospital study. more
Gap exists between vision for electronic medical records to improve care coordination and clinicians' experiences
A gap exists between policy makers' expectations that current commercial electronic medical records (EMRs) can improve coordination of patient care and clinicians' real-world experiences with EMRs, according to a study by the Center for Studying Health System Change (HSC) published online in The Journal of General Internal Medicine.
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