Developing safer, more effective drugs to fight obesity
Safer and more effective drugs to fight obesity appear to be around the corner, but researchers still await a complete understanding of the biological underpinnings of the complex disease.
Device protects transplanted pancreatic cells from the immune system
Scientists at Burnham Institute for Medical Research (Burnham) and the University of California San Diego (UC San Diego) School of Medicine have demonstrated in mice that transplanted pancreatic precursor cells are protected from the immune system when encapsulated in polytetrafluorethylene (PTFE). The study, which suggests a new approach to treating Type 1 diabetes, was published online on April 8 in the journal Transplantation. more
Treatment for acid reflux does not improve asthma
New research suggests that a widely used treatment for persistent acid reflux among asthmatics doesn’t actually improve their quality of life. The finding that as many as one-third of those studied showed no improvement makes a strong case arguing that physicians should change how they currently treat these patients. more
Cancer survivors and their doctors have different expectations about care
A new survey of oncologists, primary care physicians, and their patients finds that it is not always clear who is responsible for meeting the medical needs of cancer survivors. more
SIRT1 takes down tumors
Yuan et al. have identified another anti-cancer effect of the "longevity" protein SIRT1. By speeding the destruction of the tumor promoter c-Myc, SIRT1 curbs cell division. The study will be published online April 13 (www.jcb.org) and will appear in the April 20 print issue of the Journal of Cell Biology.
New insights into progressive hearing loss
In parallel studies in human and mouse, two groups of researchers have come to the same conclusion: that a new kind of gene is associated with progressive hearing loss. The new gene - called a microRNA - is a tiny fragment of RNA that affects the production of hundreds of other molecules within sensory hair cells of the inner ear. more
New alternative to biopsy detects subtle changes in cancer cells, Stanford study shows
A drop of blood or a chunk of tissue smaller than the period at the end of this sentence may one day be all that is necessary to diagnose cancers and assess their response to treatment, say researchers at the Stanford University School of Medicine. more
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