Volume 12 Issue 5
Published - 14:00 UTC 08:00 EST 5-Jan-2010 
Next Update - 14:00 UC 08:00 EST 6-Jan-2010






Editor: Susan K. Boyer, RN
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New ALS drug slips through telling 'phase II' clinical trials

A drug already used to treat symptoms of epilepsy has potential to slow the muscle weakening that comes with amyotrophic lateral sclerosis (ALS), scientists report after completing a Phase II clinical trial—an early, small-scale test to show if the drug works and continues to be safe. more  

Radiofrequency ablation safe and effective for reducing pain from bone metastases

Image-guided radiofrequency ablation (RFA), a minimally invasive cancer treatment which can be performed in the outpatient setting, significantly reduced the level of pain experienced by cancer patients with bone (osseous) metastases, limiting the need for strong narcotic pain management, and supporting improved patient frame of mind, according to results of an American College of Radiology Imaging Network (ACRIN) study published online in the journal Cancer. more

Pain management failing as fears of prescription drug abuse rise

Millions of Americans with significant or chronic pain associated with their medical problems are being under-treated as physicians increasingly fail to provide comprehensive pain treatment – either due to inadequate training, personal biases or fear of prescription drug abuse. more  

Researchers develop “nano cocktail” to target and kill tumors

A team of researchers in California and Massachusetts has developed a “cocktail” of different nanometer-sized particles that work in concert within the bloodstream to locate, adhere to and kill cancerous tumors. more

New key factor identified in the development of Alzheimer's disease  

Inheritance of an extra copy of the gene- ß -amyloid precursor protein, APP, in individuals with Down syndrome leads to the inevitable development of early onset Alzheimer's disease, known to be linked to the deposition of Amyloid ß peptide or Aß in the brain. However, a new study published online by Proceedings of the National Academy of Sciences identifies ßCTF, a small protein found in APP, as a novel factor for the development of Alzheimer's disease related endosome abnormalities, which have also been tied previously to the loss of brain cells in Alzheimer's disease. more

Blocking inflammation receptor kills breast cancer stem cells, U-M study finds  

Scientists at the University of Michigan Comprehensive Cancer Center have uncovered an important link between inflammation and breast cancer stem cells that suggests a new way to target cells that are resistant to current treatments. more

New research findings may help stop age-related macular degeneration at the molecular level

Researchers at University College London say they have gleaned a key insight into the molecular beginnings of age-related macular degeneration, the No. 1 cause of vision loss in the elderly, by determining how two key proteins interact to naturally prevent the onset of the condition. more

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New ALS drug slips through telling 'phase II' clinical trials