Vidyya Medical News Service
Volume 5 Issue 177 Published - 14:00 UTC 08:00 EST 26-June-2003 Next Update - 14:00 UTC 08:00 EST 27-June-2003
little clear gif used for spacer

First prostate cancer prevention drug found, but not all men benefit: NCI announces results of prostate cancer prevention trial
Men who took finasteride, a drug that affects male hormone levels, reduced their chances of getting prostate cancer by nearly 25 percent compared to men who took a placebo, according to results of a national study.  more

Prostate cancer prevention trial (pcpt): Questions and answers
The Prostate Cancer Prevention Trial, or PCPT, was a study designed to see whether the drug finasteride (trade name Proscar) could prevent prostate cancer in men ages 55 and older. The study began in October 1993 at 221 sites across the United States. The PCPT was expected to continue until May 2004, but was stopped in June 2003 when an analysis showed that finasteride reduced the risk of developing prostate cancer by 25 percent. more


Information for clinicians: Phase III randomized, double-blind, placebo-controlled study of finasteride (Proscar) for the chemoprevention of prostate cancer
The objective of the trial was to determine the efficacy (i.e., decrease in tumor initiation, promotion, or progression rate) of long-term (7-year) treatment with finasteride (Proscar, MK-906) in reducing the incidence of prostate cancer in men aged 55 and older.  more

Prescribing information: Proscar (finasteride)
Proscar lowers levels of a key hormone called DHT (dihydrotestosterone), which is a major cause of prostate growth. Lowering DHT leads to shrinkage of the enlarged prostate gland in most men. Get the full prescribing information for this drug in today's issue of Vidyya.  more

Information for patients: The prostate cancer prevention trial at-a-glance
Get the information you need about the prostate cancer prevention trial with this one-page, easy-to-read, summary. This summary appears courtesy of the National Cancer Institute.  more

little clear gif used for a space