Vidyya Medical News Service
Volume 5 Issue 213 Published - 14:00 UTC 08:00 EST 1-Aug-2003 Next Update - 14:00 UTC 08:00 EST 2-Aug-2003
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Fortifying foods with folic acid may not reduce the incidence of Down Syndrome
University of Toronto researchers have found that fortifying foods with folic acid may not reduce the incidence of Down Syndrome. But they suggest we may to need to wait another 20 years or so for the next generation of women to give birth before the real answer is known.  more

Dengue infection more serious for elderly persons
Older people who become infected with the dengue virus are more likely to need hospitalization, are more likely to suffer more severe forms of the infection, and are more likely to die compared to any other age group except infants. The findings are a part of the first research study that analyzed the clinical manifestations of dengue infection among persons 65 and older.  more


Regimens of paclitaxel and carboplatin are reasonably tolerated and efficacy is promising
According to findings published in the Aug. 1 issue of the Journal of Clinical Oncology, weekly regimens of paclitaxel in combination with full doses of carboplatin is reasonably well tolerated and the efficacy results appear promising. The study, led by Chandra P. Belani, M.D., professor of medicine, University of Pittsburgh and co-director, Lung Cancer Program, University of Pittsburgh Cancer Institute (UPCI), compared three regimens of weekly paclitaxel plus carboplatin in patients with advanced non-small cell lung cancer (NSCLC) and found that higher weekly doses of paclitaxel in combination therapy for lung cancer did not result in an added benefit for patients and caused a higher incidence of adverse side effects.  more

Changing smoking behavior by changing dopamine levels in the brain
NIDA-supported researchers have demonstrated that lowering and raising the concentration of dopamine in the brain changes smoking behavior and nicotine intake in smokers. After taking a chemical compound that blocks release of dopamine to the brain's pleasure center, smokers lit up sooner and smoked more cigarettes than they did after taking a compound that stimulates dopamine release. more

The search for clues: Why are ADHD medications protective against future substance abuse?
More than 2 million American children--an estimated 5 to 10 percent of preteens--have been diagnosed with attention-deficit/hyperactivity disorder (ADHD). For many of these children, treatment with psychostimulant medications such as Ritalin (methylphenidate, or MPH) suppresses the impulsivity, fidgeting, and inability to concentrate that characterize the disorder. Appropriate use of psychostimulants in children with ADHD also has been shown to reduce the likelihood that these children will develop drug or alcohol use disorders when they reach adolescence and adulthood.  more

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