Vidyya Medical News Service
Volume 5 Issue 307 Published - 14:00 UTC 08:00 EST 3-Nov-2003 Next Update - 14:00 UTC 08:00 EST 4-Nov-2003
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Breast cancer reversed in laboratory mice
Breast cancer researchers have demonstrated for the first time that it is possible to block genetic switches in mice that turn cancer on and off thus preventing and even reversing breast cancer in the animals. The findings, reported Sunday morning at the 24th Congress of the International Association for Breast Cancer Research, suggest potential new molecular targets for drugs to prevent and potentially eradicate breast cancer in humans.  more

Obesity gene offers explanation for overeating
An international team of researchers has identified the role of a gene which may explain why some people overeat and become obese. Their research, published today in Public Library of Science Biology, shows that the gene GAD2 has an appetite stimulating role, and that one form of the gene is strongly associated with obese people.  more


Breast cancer patients who chose lumpectomies need indefinite follow-up
Young breast cancer patients who have breast conserving treatment are at higher risk of recurrence many years later than are older women who have the same treatment or women who have mastectomies, according to research published today (Monday 3 November) in Annals of Oncology.  more

Drug Improves Brain Structure in Alzheimer's Patients
Researchers at Duke University Medical Center have determined that a medication commonly prescribed for mild to moderate Alzheimer's disease (AD) appears to cause physical improvements in the hippocampus and other brain regions of patients with the disease. These improvements could explain why the drug, donepezil (trade name Aricept), a cholinesterase inhibitor, is beneficial in treating the symptoms of some Alzheimer's patients, the researchers said.  more

Prescribing information: Aricept (donepezil)
Aricept is indicated for mild to moderate Alzheimer's disease. Aricept is well tolerated, but may not be for everyone. Some people may experience nausea, diarrhea, not sleeping well, vomiting, muscle cramps, feeling very tired, or not wanting to eat. Additional side effects that occurred in 1 or more of the studies presented in this website include those in table 3 of the Aricept package insert and also: abrasions, feeling very weak, upset stomach, headache, joint pain, dizziness, accidental injury, and urinary tract infection. In studies, these side effects were usually mild and went away over time. Get the full prescribing information in today's issue of Vidyya.  more

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