Vidyya Medical News Service
Volume 5 Issue 342 Published - 14:00 UTC 08:00 EST 8-Dec-2003 Next Update - 14:00 UTC 08:00 EST 9-Dec-2003
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Use of ximelagatran in acute venous thromboembolism is safe and effective
The use of ximelagatran in patients with acute venous thromboembolism is as safe and effective as the current standard treatment of enoxaparin, according to a study presented yesterday during the 45th Annual Meeting of the American Society of Hematology (ASH). Ximelagatran is a novel oral direct thrombin inhibitor that, in its activated form, selectively inhibits free and clot-bound thrombin, a key enzyme in the body's coagulation pathway.  more

Genes may help predict outcome in childhood leukemia
The measurement of new genes at diagnosis in children with acute lymphoblastic leukemia (ALL), discovered through new technologies from the human genome project, may be highly predictive of therapeutic outcomes.  more


OHSU Study: Three months is too soon to judge a CML patient's response to Gleevec
Gleevec has been shown to wipe out leukemia cells in 75 percent of the chronic myeloid leukemia (CML) patients who are treated with it. What oncologists haven't known is how long patients should take Gleevec before its effectiveness can be gauged. more

Addition of rituximab to standard chemotherapy does not influence response rates in older lymphoma patients
Adding rituximab to the standard chemotherapy regimen for lymphoma patients, CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone), does not significantly increase survival in older patients with diffuse large B-cell lymphoma, according to a study presented today during the 45th Annual Meeting of the American Society of Hematology (ASH).  more

Aspirin use safe and effective in patients with abnormal red cell counts (or with polycythemia)
The use of low-dose aspirin significantly reduces the risk of thrombosis in patients with polycythemia vera, an abnormal increase in blood cells resulting from excess production by the bone marrow. more

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