Vidyya Medical News Service
Volume 5 Issue 4 Published - 14:00 UTC 08:00 EST 4-Jan-2003 Next Update - 14:00 UTC 08:00 EST 5-Jan-2003
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Potential new treatment for people with manic depression
AstraZeneca has announced that it has submitted an application to the U.S. Food and Drug Administration (FDA) for quetiapine (Seroquel) to be granted a licence for the treatment of acute mania associated with bipolar disorder (manic-depressive illness).  more

Prescribing information: Seroquel (quetiapine)
The most common adverse events associated with the use of Seroquel are dizziness (10%), postural hypotension (7%), dry mouth (7%), and dyspepsia (6%). The majority of adverse events are mild or moderate. The incidence of somnolence in clinical trials was 18% versus 11% for placebo. more


Nicotine - Worse than we thought?
Cigarettes are addictive, and smoking them causes lung cancer. Of the two "active ingredients" listed on the packs, scientists had initially assumed that nicotine was the addictive agent, and tar the carcinogen. Recent evidence, however, suggests that things are not that simple, and that nicotine and its derivatives themselves might also promote cancer development and progression. Phillip Dennis and colleagues at the US National Cancer Institute in Bethesda, have studied the effect of nicotine and the nicotine-derived nitrosamine NKK on normal lung epithelial cells--i.e. those cells that are exposed to inhaled smoke and in which lung cancer starts. more

New study shows angioplasty more effective than clot busters in treating heart attack
Angioplasty offers a better prognosis than clot-dissolving medications for treating patients with the deadliest type of heart attack, report researchers at UT Southwestern Medical Center at Dallas. more

The making of a disease: female sexual dysfunction
Drug companies are sponsoring creation of a new medical disorder known as female sexual dysfunction in order to build markets for drugs among women, despite controversy surrounding the medicalisation of sexual problems, finds an article in this week's BMJ.  more

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