Vidyya Medical News Service
Volume 6 Issue 187 Published - 14:00 UTC 08:00 EST 5-Jul-2004 Next Update - 14:00 UTC 08:00 EST 6-Jul-2004
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3-D structure of anthrax toxin complex solved
Scientists have determined a three-dimensional (3-D) molecular image of how anthrax toxin enters human cells, giving scientists more potential targets for blocking the toxin, the lethal part of anthrax bacteria. The finding also points to a possible way to design anthrax toxin molecules that selectively attack tumor cells, as described in the journal Nature published online July 4. The study, funded by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, was led by Robert C. Liddington, Ph.D., of the Burnham Institute in La Jolla, CA.  more

Severe sepsis causes almost 10% of cancer deaths
Severe sepsis, is a costly complication in hospitalized cancer patients causing around one in ten cancer deaths each year in the USA, according to an article published today in Critical Care. The excessive response to infection in patients with severe sepsis injures critical organs such as the lungs and kidneys. more

Stress affects immunity in ways related to stress type and duration
Psychologists have long known that stress affects our ability to fight infection, but a major new "meta-analysis" a study of studies has elucidated intriguing patterns of how stress affects human immunity, strengthening it in the short term but wearing it down over time. The report appears in the July issue of Psychological Bulletin, which is published by the American Psychological Association.  more


Combination of gene therapy and gene silencing prevents neurodegenerative disease
University of Iowa researchers have shown for the first time that gene therapy delivered to the brains of living mice can prevent the physical symptoms and neurological damage caused by an inherited neurodegenerative disease that is similar to Huntington's disease (HD).  more

Vitamin D: Total intake can reduce colorectal cancer mortality
Studies of the geographic variation of colon and rectal (colorectal) cancer mortality rates in the U.S. have long indicated that they are primariliy linked to solar ultraviolet-B (UVB) radiation: the more UVB in summer, the lower the mortality rate.  more

Vacuum assisted deliveries are safe alternative to forceps
Vacuum assisted deliveries are a safe alternative to forceps deliveries, despite a warning by the US Food and Drug Administration in 1998 that vacuum assisted deliveries may result in fatal complications, say researchers in this week's BMJ.  more

Better information needed about herb-drug interactions
Doctors and patients should beware of possible interactions of St John's wort with conventional drugs, but better information is needed to guide clinical practice, say researchers in this week's BMJ. more

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