Vidyya Medical News Service
Volume 6 Issue 217 Published - 14:00 UTC 08:00 EST 4-Aug-2004 Next Update - 14:00 UTC 08:00 EST 5-Aug-2004
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Depression traced to overactive brain circuit
A brain imaging study by the NIH's National Institute of Mental Health (NIMH) has found that an emotion-regulating brain circuit is overactive in people prone to depression -- even when they are not depressed. Researchers discovered the abnormality in brains of those whose depressions relapsed when a key brain chemical messenger was experimentally reduced. Even when in remission, most subjects with a history of mood disorder experienced a temporary recurrence of symptoms when their brains were experimentally sapped of tryptophan, the chemical precursor of serotonin, the neurotransmitter that is boosted by antidepressants.  more

New study to show how rheumatoid arthritis patients rate improvement change
A new clinical study to determine how people with rheumatoid arthritis (RA) evaluate improvements in disease symptoms will be carried out by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), part of the Department of Health and Human Services' National Institutes of Health. The study will examine how much of an improvement in pain, stiffness, function and other symptoms is needed before patients consider the change important.  more

Best approach to taking out thyroid may be under the arm, study shows
The best approach to removing a diseased thyroid, the endocrine gland just under the Adam’s apple that controls the body’s metabolic rate, amazingly may be from under the arm, according to a study published in the August issue of the journal Laryngoscope. more


FDA approves Sculptra (injectable filler to correct facial fat loss) for HIV patients
After an expedited review, the Food and Drug Administration (FDA) today approved an injectable filler to correct facial fat loss in people with human immunodeficiency virus (HIV) infection.  more

Prescribing information: Sculptra
Sculptra is injected into the skin for restoration and/or correction of the signs of facial fat loss (lipoatrophy) in people with human immunodeficiency virus. Sculptra™ should not be injected while there are signs of an active skin infection or inflammation in the treatment area. Side effects of Sculptra may include the delayed appearance of small bumps under the skin in the treated area. Generally these bumps are not visible and may only be noticed when pressing on the treated area. Other side effects may include injection-related events at the site of injection, such as bleeding, tenderness or discomfort, redness, bruising or swelling. Get the full prescribing information in today's issue of Vidyya.  more

Babies with DiGeorge Syndrome saved by immune supression, thymus transplant
Duke University Medical Center researchers have developed a combination immune suppression and thymus transplantation technique to save infants born with complete DiGeorge Syndrome, a fatal genetic disorder.  more

Gun laws requiring safe storage prevent some youth suicides
A new study conducted by researchers at the Johns Hopkins Bloomberg School of Public Health provides evidence that the child access prevention (CAP) laws for firearms enacted by 18 U.S. states significantly reduced suicide rates among young people 14 to17 years old. CAP laws require gun owners to store their guns so as to prevent unsupervised access by children. The study is published in the August 4, 2004, issue of the Journal of the American Medical Association (JAMA).  more

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