Vidyya Medical News Service
Volume 6 Issue 276 Published - 14:00 UTC 08:00 EST 2-Oct-2004 Next Update - 14:00 UTC 08:00 EST 3-Oct-2004
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Hostility personality trait predicts brain metabolic response to nicotine
Dr. Steven Potkin and colleagues at the University of California, Irvine, administered personality tests to 31 smokers and 55 nonsmokers. Participants were grouped according to hostile (anger, impatience, irritability, nervousness) or nonhostile (happy, relaxed, and curious) personality traits. All hostile and nonhostile smokers and nonsmokers received a low-dose nicotine patch, as well as a placebo.  more

Cigarette smoke causes breaks in DNA and defects to a cell's chromosomes
The amount of smoke in just one or two puffs of a cigarette can cause breaks in DNA and defects to a cell's chromosomes, leading to irreversible changes in genetic information being passed to a newly divided cell, according to University of Pittsburgh researchers. Their findings, to be reported Tuesday, Oct. 5 at the 35th Annual Meeting of the Environmental Mutagen Society, are the first to show that cigarette smoke causes chromosome instability.  more

Large-scale tonsilectomy study would quantify UK CJD prevalence
A study in this week’s issue of The Lancet describes how two different types of analysis used in conjunction on samples of tonsil tissue is the ‘gold standard’ method for confirming clinical variant CJD, and that a large-scale screening program of tonsil tissue is the only way of identifying the true incidence of vCJD infection. more


Vitamin supplements no benefit against gastro-intestinal cancer
A systematic review and meta-analysis (pooled analysis) of previously published randomized trials in this week’s issue of The Lancet provides strong evidence that antioxidant supplements (such as vitamin supplements) are not effective in protecting against gastro-intestinal cancer. Some combinations of supplements may slightly increase gastro-intestinal cancer risk, whereas selenium may be associated with a risk reduction.  more

Sociologists to map disease, death by analyzing prescription drugs
Last year, Mississippi State medical sociologist Lynne Cossman and medical geographer Ronald Cossman released a detailed report spotlighting clusters of “healthy” and “unhealthy” places throughout the United States.  more

Study shows colorectal cancer risk higher in people with insulin-requiring type 2 diabetes
A study published today in the American Gastroenterological Association's journal Gastroenterology concludes that patients with type 2 diabetes mellitus who require long-term insulin therapy are at a significantly increased risk for colorectal cancer. more

Radiologists call for judicious use of CT for detecting pulmonary embolism
There has been a striking increase in the number of patients undergoing CT examinations of the chest to look for clots in the lung (pulmonary embolism) over recent years, especially through the emergency department, a study at one facility shows. This increased usage in combination with the radiation doses and the fact that new scanners can show previously undetectable abnormalities that may or may not affect treatment has radiologists calling for judicious ordering of the exam.  more

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