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Some antibiotic resistance threat in hospitals could yield to hand washing
Johns Hopkins researchers report potentially life-threatening hospital infections with bacteria resistant to the antibiotic methicillin can occur even if patients haven't been treated with that drug. But, they add, these infections can be stopped with one of medicines oldest and most powerful antibacterial treatments: hand washing. more
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Fosrenol (R)maintains bone health status of end-stage renal disease patients
Long-term treatment with Fosrenol (R) (lanthanum carbonate), a new non-calcium, non-aluminum phosphate binder, does not promote bone softening or cause harmful effects on bone, according to data presented this week at the American Society of Nephrology (ASN) annual meeting in St. Louis, Mo. more
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Prescribing information: Fosrenol (R) (lanthanum carbonate)
Lanthanum carbonate dissociates in the acid environment of the upper GI tract to release lanthanum ions that bind dietary phosphate released from food during digestion. Fosrenol (R) inhibits absorption of phosphate by forming highly insoluble lanthanum phosphate complexes, consequently reducing both serum phosphate and calcium phosphate product. more
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Gene-silencing technique offers new way to fight drug-resistant leukemia
Ever since the approval of Gleevec in 2001, a cancer-cell-specific drug used to treat chronic myelogenous leukemia (CML), the field of cancer therapeutics has been rushing full speed into the era of so-called "targeted" medicines. The challenge of developing these medicines, which spare normal cells because they are designed to kill only cancer cells, has been complicated by the recognition that resistance to even targeted therapies can develop. more
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Scientists discover enzyme crucial to HIV replication
Scientists have discovered that a cellular enzyme helps ferry HIV genetic instructions out of the cell nucleus where they can then be translated into proteins to begin their most destructive work. The cellular enzyme represents a potential new target for developing improved HIV drugs, say the researchers from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and the McGill University AIDS Center. more
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Drug combination (Pegasys (R) and ribavirin) shows promise in treating hepatitis C
Researchers at Saint Louis University School of Medicine and six other research sites throughout the country found that combining the drug Pegasys® with ribavirin resulted in a greater reduction in hepatitis C viral levels than patients treated with Peg-Intron® and an equal dose of ribavirin. more
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Prescribing information: Pegasys (pegylated interferon)
Pegasys is a pegylated form of interferon alfa-2a. Pegasys is a treatment option for hepatitis C patients and is currently the only pegylated interferon available as a ready-to-use solution. more
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