Vidyya Medical News Service
Volume 7 Issue 15 Published - 14:00 UTC 08:00 EST 15-Jan-2005 Next Update - 14:00 UTC 08:00 EST 16-Jan-2005
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* Vanderbilt researchers make microfluidic devices out of a plastic similar to that used in soft contact lenses. Credit: By Neil Brake, Vanderbilt University

Vanderbilt University develops portable infectious disease detector
A portable device similar to today's home pregnancy tests that can quickly detect the presence of infectious diseases, including HIV-AIDS and measles, as well as biological agents such as ricin and anthrax, is the object of a new joint university/industry research project.  more

FDA approves Enablex for treatment of overactive bladder
In late December, Novartis Pharmaceuticals Corporation announced that the U.S. Food and Drug Administration (FDA) has approved Enablex® (darifenacin) extended-release tablets (7.5mg and 15mg) for the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency and frequency. Enablex, a once-daily medication, is expected to launch in the U.S. in early 2005.  more

Prescribing information: Enablex (darifenacin) extended-release tablets (7.5mg and 15mg)
Enablex works by blocking the M3 receptor, which is primarily responsible for bladder muscle contraction. It is a potent muscarinic receptor antagonist that helps reduce incontinence episodes, increases the amount of urine the bladder can hold, reduces the frequency of urination episodes, and decreases the pressure or urgency associated with the urge to urinate.  more


COX-2 levels elevated in smokers
Tobacco smoke triggers the production of COX-2, a cellular protein linked to the development and progression of cancer.  more

Depression caused by common treatment for hepatitis C
An article appearing in the January 2005 issue of Brain, Behavior and Immunity suggests that developing depression while on interferon-alpha plus ribavirin may impact how well the medications work.  more

Found: Missing sequence of the human Y chromosome
Scientists report today in the journal Genome Research that they have successfully cloned and characterized a previously intractable DNA sequence: a 554-kilobase-pair genomic segment near the centromere of the human Y chromosome. This sequence contains eight putatively active genes that could be implicated in sex-associated height differences and gonadal tumor development. more

New theory chalenges current view of how brain stores long-term memory
How do you remember your own name? Is it possible ever to forget it? The memory trace, or engram, "feels" like it is stored permanently in the brain and it will never be forgotten. more

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