Volume 7 Issue 228
Published - 14:00 UTC 08:00 EST 16-Aug-2005 
Next Update - 14:00 UTC 08:00 EST 17-Aug-2005

Editor: Susan K. Boyer, RN
Vidyya.
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New heart failure guidelines stress early diagnosis and treatment

Early diagnosis and new treatments can help battle heart failure -- a growing national problem that causes 1 million hospital admissions each year, according to new guidelines released today by the American College of Cardiology (ACC) and the American Heart Association (AHA). more  

U of M researchers show that increasing sugar processing in the liver can lower blood sugar

Researchers at the University of Minnesota have shown that increasing the concentration of a key regulator involved in glucose metabolism can improve the way the liver produces and disposes of the sugar glucose, the primary fuel of the body. Finding ways to increase that concentration could provide a treatment for diabetes and obesity. The research will be published in the Aug. 16 issue of Cell Metabolism. more

Driving metastasis

Metastasis is the primary cause of deaths in cancers. Published in the September 1 issue of G&D, Dr. Tak Mak and colleagues have successfully generated a strain of RhoC-deficient mice, providing long-awaited in vivo confirmation of RhoC's critical role in tumor metastasis. more  

Kidney failure a significant cause of ICU deaths worldwide

In the first multinational study of acute renal failure (ARF) in ICU patients, an international group of researchers has found that a surprisingly high number of intensive care patients one in 20 develop a severe form of ARF, and an alarmingly high number of those patients will die in the hospital. The study is published in the August 17 issue of the Journal of the American Medical Association. more

Hospital heart attack treatment during off-hours and poorer outcomes  

Patients who arrive at a hospital during off-hours and on the weekend following a heart attack have longer times to the restoration of normal blood flow and a higher risk of death, according to a study in the August 17 issue of JAMA. more

Treatments have same target, different responses for lung cancer patients with genetic mutation 

The gene mutation that identifies the lung cancer patients most likely to respond to the drug gefitinib (Iressa) is not associated with a response to the drug cetuximab (Erbitux), according to a new study published in the August 17 issue of the Journal of the National Cancer Institute. Both drugs target the same gene but through different mechanisms. more

Heart failure worsens with anemia, increases risk of death

Low hemoglobin levels are a predictor of increased risk of death and complications among heart failure patients, according to a report in Circulation: Journal of the American Heart Association. Hemoglobin (Hgb) is the major substance in red blood cells, and its level indicates the blood's ability to carry oxygen throughout the body. Studies have shown that low hemoglobin, which may result in anemia, is more common among patients with heart failure than it is among people in the general population. more

 

A surprisingly high number of intensive care patients one in 20 develop a severe form of acute renal failure