Volume 7 Issue 343
Published - 14:00 UTC 08:00 EST 28-Dec-2005 
Next Update - 14:00 UTC 08:00 EST 29-Dec-2005

Editor: Susan K. Boyer, RN
Vidyya.
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First analysis of FDA's mifepristone Adverse Event Reports

The abortion drug mifepristone (Mifeprex,TM RU-486), initially touted as a more convenient alternative to surgical abortion, has been linked to serious adverse reactions, including several deaths in otherwise healthy women. more  

Bipolar disorder more common than expected in hospitalized adolescents

Clinicians at Bradley Hospital, the nation's first psychiatric hospital for children and adolescents, have found that bipolar disorder is more common than expected in teens in a psychiatric inpatient setting. more

Flexible drug dosing produces less side-effects in people with epilepsy

For the first time, researchers compared dosing regimens of an antiepileptic drug (AED) used for treatment of partial epilepsy in adults, in conjunction with other AEDs. They looked at dosing used in clinical everyday life (flexible dosing) and that used in classical clinical trials (fixed dose) and discovered that the flexible dosing method was superior. more  

Vitamin D needed to cut cancer risk

Taking 1,000 international units (IU) of vitamin D3 daily appears to lower an individual's risk of developing certain cancers including colon, breast, and ovarian cancer by up to 50 percent, according to cancer prevention specialists at the Moores Cancer Center at the University of California, San Diego (UCSD) Medical Center. The researchers call for prompt public health action to increase intake of vitamin D3 as an inexpensive tool for prevention of diseases that claim millions of lives each year. more

Dietary intake of antioxidants associated with reduced risk of age-related macular degeneration  

A diet with a high intake of beta carotene, vitamins C and E, and zinc is associated with a substantially reduced risk of age-related macular degeneration in elderly persons, according to a study in the December 28 issue of JAMA. more

Misdosing common for powerful anti-clotting drugs 

Because of inaccuracies in prescribing, 42 percent of patients rushed to emergency rooms with symptoms of a heart attack received doses of powerful drugs intended stop clotting in coronary arteries outside of the recommended range, a new analysis by Duke Clinical Research Institute (DCRI) cardiologists has found. more

Natural compound from 'pond scum' shows potential activity against Alzheimer's

A compound isolated from a cyanobacterium, a type of blue-green algae known as Nostoc, shows promise of becoming a natural drug candidate for fighting Alzheimer's and other neurodegenerative diseases, according to an in vitro study by researchers in Switzerland. It is believed to be the first time that a potent agent against Alzheimer's has been isolated from cyanobacteria, commonly known as 'pond scum.' The study was published in the Dec. 26 issue of the Journal of Natural Products, a monthly peer-reviewed joint publication of the American Chemical Society and the American Society of Pharmacognosy. more

 

This first published analysis of the FDA's mifepristone reports describes 607 adverse events reported over a 4-year period, including fatalities resulting from bleeding or septic shock.