Volume 8 Issue 149
Published - 14:00 UTC 08:00 EST 29-May-2006 
Next Update - 14:00 UTC 08:00 EST 30-May-2006

Editor: Susan K. Boyer, RN
© Vidyya.
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Boosting the supply of key breast cancer stem cells

The key to developing more effective ways to diagnose and treat breast cancer will probably involve targeting Breast Cancer Stem Cells (BrCSCs), a small population of tumor cells that resemble adult stem cells. Scientists long have thought that all the cells in a malignant tumor divide abnormally -- a hallmark of cancer. However, recent evidence strongly suggests that only a small population of cells, including BrCSCs in breast cancer, is endowed with that ability. more  

Bourbon on the briquettes

Charcoal, that well-known ingredient for summer cookouts, also is the secret ingredient for making whiskey. Charred wood on the inside of whiskey barrels changes freshly distilled spirits from a colorless, harsh-tasting, yuk! into that familiar sipping-smooth beverage. Charcoal also finds use -- counterproductively, in fact -- to filter and clarify cloudy whiskey. (You'd get a more flavorful beverage if distillers skipped that for-aesthetics-only step and marketed cloudy whiskey.) more

New drug nanocarriers for nanomedicine

The great promise of nanomedicine in opening a new era in diagnosis and treatment of disease depends heavily on the availability of versatile nanocarriers. The ultra-small counterparts of hypodermic syringes and IVs, nanocarriers are the containers that will carry and deliver nanodiagnostic and nanotherapeutics to their targets inside the human body. more  

Profiling muscle loss in aging

The age-related loss of muscle mass and strength called sarcopenia is getting more attention as the first of 76 million baby boomers turn 60 this year. A slow, barely noticeable loss of muscle begins around age 30. The rate increases sharply around age 60. As sleek, firm muscle disappears, older people become more vulnerable to falls and disabling hip fractures, and are less able to perform everyday tasks and continue living independently. more

Differences in sexual desire can be attributed to genetic variances 

New evidence that individual differences in human sexual desire can be attributed to genetic variations has been revealed by a research group headed by a professor of psychology at the Hebrew University of Jerusalem. The findings are believed to have an impact on people's understanding of their own sexuality as well as to how sexual disorders may come to be treated in the future. more

New understanding of COX-1 and COX-2 enzymes could lead to revised classification of pain meds, Queen’s study shows  

COX-1 and COX-2 enzymes may be blocked by pain medications such as Advil and Vioxx in a more complex manner than was previously understood, a Queen’s University study has found. more

Researchers in Munich discover a cellular mechanism that can protect against tumours

When protective mechanisms in cells fail, certain genes can cause tumours - and cancer. One of these oncogenes is Bcl-3, which can lead to leukaemia, among other diseases. Scientists from the Max Planck Institute of Biochemistry in Martinsried, Germany, working with colleagues at the Ludwig Maximilians University of Munich (LMU), have discovered a mechanism which activates and regulates Bcl-3. Reinhard Fässler led a team which has published an article on this topic in the latest edition of Cell. A protein called Cyld controls Bcl-3 - and thus protects mice from tumour growth. The researchers were able to describe the cellular signalling path which causes uncontrolled growth when the Cyld gene is defective. Furthermore, there is evidence that such a defective Cyld gene may be the root cause of kidney, liver, uterus, and large intestine tumours. Cyld could possibly be one of Bcl-3's most important opponents - in mice and men (Cell, May 19 2006). more

 

Charcoal, that well-known ingredient for summer cookouts, also is the secret ingredient for making whiskey.