Depression: New therapy gives reason for hope
A study at the University Clinics of Bonn and Cologne gives people with therapy-resistant depression reason for hope. The doctors treated two men and a woman with what is known as deep brain stimulation. All three patients have been suffering from very severe depression for several years which could neither be brought under control using medication nor by other therapies. During the simulation the condition of two of the three patients improved within a few days. Initial changes were even noticeable in a matter of minutes. The research team warn against exaggerated expectations in view of the small number of patients involved. Nevertheless, the results of the preliminary study are so sensational that they have now been published in the renowned journal Neuropsychopharmacology.
Changing to a low-fat diet can induce stress
Changing one's diet to lose weight is often difficult. There may be physical and psychological effects from a changed diet that reduce the chances for success. With nearly 65% of the adult population currently classified as overweight or obese and with calorically dense foods high in fat and carbohydrates readily available, investigating those factors that contribute to dieting failures is an important effort. In a study in the May 1st issue of Biological Psychiatry, researchers found that mice withdrawn from high-fat or high-carbohydrates diets became anxious and showed changes in their brains indicating higher stress levels. more
Intravenous nanoparticle gene therapy shows activity in stage IV lung cancer
A cancer-suppressing gene has been successfully delivered into the tumors of stage 4 lung cancer patients via an intravenously administered lipid nanoparticle in a phase I clinical trial at The University of Texas M. D. Anderson Cancer Center. The gene, FUS1, also was found to be active in the metastatic non-small cell lung cancer tumors. more
Pancreatic cancer vaccine halts progression of disease in some patients
A dendritic cell-based therapeutic vaccine for pancreatic cancer developed by researchers at the University of Pittsburgh School of Medicine has successfully stalled the disease from progressing in a handful of patients three years post-vaccination. The results, part of a press briefing on cancer vaccines held at the annual meeting of the American Association of Cancer Research in Los Angeles, provide promising evidence that the vaccine can trigger a patient’s own immune system to rally against pancreatic cancer and offer new insights into how the vaccine could be made even more effective. The study is abstract number 4896 in the meeting proceedings. more
Traditional Chinese medicinal herbs may help women with breast cancer
Using Chinese herbs either alone or in conjunction with chemotherapy may help protect a breast cancer patient's bone marrow and immune system, as well as improving the woman's overall quality of life.
Popular herbal supplement hinders the growth of pancreatic cancer cells
A new study from the University of Pittsburgh Cancer Institute suggests that a commonly used herbal supplement, triphala, has cancer-fighting properties that prevent or slow the growth of pancreatic cancer tumors implanted in mice. The study found that an extract of triphala, the dried and powdered fruits of three plants, caused pancreatic cancer cells to die through a process called apoptosis – the body’s normal method of disposing of damaged, unwanted or unneeded cells. more
Omega-3 fatty acid may help prevent Alzheimer's brain lesions
A type of omega-3 fatty acid may slow the growth of two brain lesions that are hallmarks of Alzheimer’s disease, UC Irvine scientists have discovered. The finding suggests that diets rich in docosahexaenoic acid (DHA) can help prevent the development of Alzheimer’s disease later in life. more
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