Gene expression profiling in mice can predict risk of skin lesions progressing to cancer
A new study has shown that microarray technology, which allows researchers to simultaneously compare the degree to which hundreds of genes are expressed (converted into proteins), now makes it possible to more definitively identify skin lesions in mice that are thought to be at high risk of progressing to a type of cancer known as squamous cell carcinoma (SCC).
Low levels of common enzyme key to resistance in Ewing’s sarcoma
A study from scientists at the University of Freiburg, Germany, and their collaborators at the National Cancer Institute (NCI), part of the National Institutes of Health, has pinpointed a potential mechanism for resistance of Ewing’s sarcoma, a type of bone cancer, to a protein that may be useful in fighting cancer — and a possible method for overcoming this resistance. The results appear online May 23, 2007, in the Journal of Pathology. more
Mice regenerate hair follicles
Researchers have rebuffed conventional wisdom and shown that adult mice can regenerate hair follicles and hair after wounding. The finding suggests new directions for designing treatments for wounds, hair loss and other degenerative skin disorders. more
Androgenetic alopecia is a common form of hair loss in both men and women. In men, this condition is also known as male-pattern baldness. Hair is lost in a well-defined pattern, beginning above both temples. Over time, the hairline recedes to form a characteristic "M" shape. Hair also thins at the crown (near the top of the head), often progressing to partial or complete baldness. more
“Entry claw” helps the HIV virus infect host cells
Scientists have described a new structure at the interface between the AIDS virus and the host cells it infects that appears to help the virus gain entry to its target.
Genetic roots of bipolar disorder revealed
The first genome-wide study of bipolar disorder has found that no single gene is sufficient to cause the disorder. Rather, several genetic variations appear to boost the disease risk, especially in combination. The implicated genes provide potential new targets for drug development and may ultimately lead to more effective treatments. more
New risk factors identified for type 2 diabetes
A collaborative effort by 3 international research teams has provided new clues to help us understand why some people develop type 2 diabetes and others do not. more
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