Study of major significance unlocks the door to the complex role of how hormones work in women and demonstrates steep decline of hormones in early reproductive years
Findings from the Australian based Jean Hailes Foundation will be presented this week at the Endocrine Society’s 86th Annual Meeting that establish normal hormone levels in women across the life span.
This definitive study is part of the Sue Ismiel
International Study into Women's Health and Hormones,
involving 1423 women aged 18 – 75, documenting how
hormone levels change as women age, and the
relationships between various hormones and lowered mood,
libido and sense of well-being.
Until now there was no base platform for androgen levels
across the female life span. “We think hormones in women
have important positive effects on mood, our general
well-being, energy levels and libido but no-one has ever
done a study in women aiming to directly relate these to
hormone levels in the blood,” said Dr Sonia Davison,
Endocrinologist at The Jean Hailes Foundation.
“Using a sensitive method to measure testosterone we
report values for women across ages from the community
and demonstrate that DHEAS, total testosterone and free
testosterone levels decline steeply in the early
reproductive years, and do not vary as a consequence of
natural menopause. “
Key outcomes of this study include:
DHEAS (sex hormones) declines
sharply in the early reproductive years
There were no changes to androgen
levels across the menopause years
Data predictions indicate that
androgens increase in older women 70+
It is of major significance to determine what normal
hormone levels are in women of all ages, especially
younger women, to relate this back to mood and sex drive
and establish what it all means for women as they
progress through life.
“We are yet to complete the Ismiel study in its entirety
and whilst this doesn’t portray the whole story just yet
we are making head way in understanding how hormones
work in women’s bodies and the impact on their health
and wellbeing,“ Dr Davison said.
The Jean Hailes Foundation is Australia’s leading
women’s health organization. This study is funded as
part of the Sue Ismiel International Study into Women’s
Health and Hormones.
*This abstract is the recipient of the prestigious
“Women in Endocrinology Abstract Award” at this years
Endocrine Society Meeting.*