Vidyya Medical News Service
Volume 6 Issue 231 Published - 14:00 UTC 08:00 EST 18-Aug-2004 Next Update - 14:00 UTC 08:00 EST 19-Aug-2004
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Clinical trial information: Treatment of Adolescent Suicide Attempters (TASA)

This study is currently recruiting patients.


The purpose of this study is to compare the effects of three types of treatments for depressed teenagers who have attempted suicide.

Condition Treatment or Intervention Phase
Major Depressive Disorder
Depressive Disorder not otherwise specified (NOS)
Dysthymic Disorder
 Drug: fluoxetine
 Drug: sertraline
 Drug: citalopram
 Drug: escitalopram
 Drug: buproprion
 Drug: mirtazapine
 Drug: venlafaxine
 Drug: lithium
 Behavior: Cognitive Behavioral Therapy
Phase II
Phase III

MedlinePlus related topics:  Mental Health

Study Type: Interventional
Study Design: Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Safety/Efficacy Study

Further Study Details: 

Suicide is the third leading cause of death in adolescents and is a major public health problem. Depression is the most common diagnosis for adolescent suicide attempts. Little is known about what treatment is best for these adolescents since they are usually excluded from participation in research studies.

Participants in this study will be randomly assigned to receive carefully monitored antidepressant medication with routine support and management, cognitive behavioral therapy (CBT), or a combination of antidepressant medication plus CBT.


Ages Eligible for Study:  12 Years   -   18 Years,  Genders Eligible for Study:  Both


Inclusion Criteria:

  • At least one suicide attempt or interrupted attempt within the past 45 days
  • Continuously reside with a primary caretaker (parent, legal guardian, foster parent) for at least 6 months that can provide legal consent

Expected Total Enrollment:  120

Location and Contact Information

Ben Vitiello, MD      301.443.4283

      Johns Hopkins University, Baltimore,  Maryland,  21287,  United States; Recruiting
Deidre Everist  410-955-7675 
John Walkup, MD,  Principal Investigator

New York
      Columbia University at the New York State Psychiatric Institute, New York,  New York,  10032,  United States; Recruiting
Lisa Capasso  212-543-6039 
Laurence Greenhill, MD  212.543.5340 
Laurence Greenhill, MD,  Principal Investigator

      New York University Child Study Center, New York,  New York,  10016,  United States; Recruiting
Lori Evans, PhD  212-263-3661 
Angela Chiu  212.263.3651 
Barbara Coffey, MD,  Principal Investigator

North Carolina
      Duke University Medical Center, Durham,  North Carolina,  27705,  United States; Recruiting
Scott Compton, PhD  919-416-2416 
Denny Hood  919.416.2410 
Karen Wells, PhD,  Principal Investigator

      University of Pittsburgh - Western Psychiatric Institute and Clinic, Pittsburgh,  Pennsylvania,  15213,  United States; Recruiting
Jamie Zelazny, RN  412-246-6124 
David Brent, MD,  Principal Investigator

      University of Texas, Southwestern Medical Center, Dallas,  Texas,  75235,  United States; Recruiting
Jenny Hughes  214-648-4397 
Graham Emslie, MD,  Principal Investigator

Study chairs or principal investigators

Laurence Greenhill, MD,  Study Chair

More Information

Study ID Numbers  1U10MH66762-01
Study Start Date March 2004
Record last reviewed  June 2004
NLM Identifier  NCT00080158 processed this record on 2004-08-17

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